Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.69 |
| ▸ | CES1 | P23141 | 2/20 | 0.65 |
| ▸ | CA1 | P00915 | 2/20 | 0.63 |
| ▸ | CA2 | P00918 | 2/20 | 0.63 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.62 |
| ▸ | CES2 | O00748 | 1/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | GSK3B | P49841 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4949082 | 1.00 | TDP1 (0.69) | TDP1CES1CA1CA2SRD5A2 | |
| SCHEMBL15180824 | 0.83 | CES1 (0.79) | TDP1CES1CA1CA2SRD5A2 | |
| SCHEMBL2099160 | 0.83 | CES1 (0.79) | TDP1CES1CA1CA2SRD5A2 | |
| SCHEMBL15347688 | 0.82 | TDP1 (0.53) | TDP1CES1CA1CA2SRD5A2 | |
| SCHEMBL15347692 | 0.82 | TDP1 (0.53) | TDP1CES1CA1CA2SRD5A2 | |
| Terephthalic Acid SCHEMBL28023943 | 0.82 | TDP1 (1.00) | TDP1CES1CA1CA2SRD5A2 | |
| 4-Nitrobenzoic Acid SCHEMBL43476 | 0.82 | TDP1 (1.00) | TDP1CES1CA1CA2SRD5A2 | |
| Hydrogen Peroxide SCHEMBL28789390 | 0.81 | ALDH1A1 (0.72) | TDP1CES1CA1CA2SRD5A2 | |
| SCHEMBL12168656 | 0.80 | MAPK1 (0.63) | TDP1CES1CA1CA2SRD5A2 | |
| 4-Nitrobenzoic Acid SCHEMBL17332065 | 0.80 | TDP1 (0.95) | TDP1CES1CA1CA2SRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9102830-B2 | Bis-(α-amino)-diol-diester-containing poly (ester amide) and poly (ester urethane) compositions and methods of use | MEDIVAS, LLC (US) | 2015-08-11 | — | — | US | disclosed |
| US-20130210931-A1 | BIS-(ALPHA-AMINO)-DIOL-DIESTER-CONTAINING POLY (ESTER AMIDE) AND POLY (ESTER URETHANE) COMPOSITIONS AND METHODS OF USE | MEDIVAS, LLC (US) | 2013-08-15 | — | — | US | disclosed |
| EP-1926780-B1 | BIS-( -AMINO)-DIOL-DIESTER-CONTAINING POLY(ESTER AMIDE) AND POLY(ESTER URETHANE) COMPOSITIONS AND METHODS OF USE | MEDIVAS LLC (US) | 2013-08-14 | — | — | EP | disclosed |
| US-8445627-B2 | Alkylene-dicarboxylate-containing biodegradable poly(ester-amides) and methods of use | MEDIVAS, LLC (US) | 2013-05-21 | — | — | US | disclosed |
| US-8445007-B2 | Bis-(α-amino)-diol-diester-containing poly (ester amide) and poly (ester urethane) compositions and methods of use | MEDIVAS, LLC (US) | 2013-05-21 | — | — | US | disclosed |
| US-20080299174-A1 | Bis-(Alpha-Amino)-Diol-Diester-Containing Poly (Ester Amide) and Poly (Ester Urethane) Compositions and Methods of Use | MEDIVAS, LLC | 2008-12-04 | — | — | US | disclosed |
| EP-1926780-A2 | BIS-( -AMINO)-DIOL-DIESTER-CONTAINING POLY(ESTER AMIDE) AND POLY(ESTER URETHANE) COMPOSITIONS AND METHODS OF USE | Medivas, LLC (US) | 2008-06-04 | — | — | EP | disclosed |
| US-20070287987-A1 | Alkylene-dicarboxylate-containing biodegradable poly(ester-amides) and methods of use | MEDIVAS, LLC (US) | 2007-12-13 | — | — | US | disclosed |
| WO-2007035938-A2 | BIS-(α-AMINO)-DIOL-DIESTER-CONTAINING POLY(ESTER AMIDE) AND POLY(ESTER URETHANE) COMPOSITIONS AND METHODS OF USE | MEDIVAS, LLC (US) | 2007-03-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080299174-A1 | Bis-(Alpha-Amino)-Diol-Diester-Containing Poly (Ester Amide) and Poly (Ester Urethane) Compositions and Methods of Use | APEH, DAO, DNPEP | TDP1 1613/4885CES1 318/4885CA1 365/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.