Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR3 | Q9UBY5 | 6/20 | 0.41 |
| ▸ | LPAR2 | Q9HBW0 | 3/20 | 0.41 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.40 |
| ▸ | FDPS | P14324 | 8/20 | 0.37 |
| ▸ | GGPS1 | O95749 | 3/20 | 0.37 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphoric Acid SCHEMBL4945577 | 1.00 | LPAR3 (0.41) | LPAR3LPAR2SIRT2FDPSGGPS1 | |
| Phosphoric Acid SCHEMBL4950070 | 1.00 | LPAR3 (0.41) | LPAR3LPAR2SIRT2FDPSGGPS1 | |
| Phosphoric Acid SCHEMBL4952420 | 1.00 | LPAR3 (0.41) | LPAR3LPAR2SIRT2FDPSGGPS1 | |
| Phosphoric Acid SCHEMBL4953040 | 1.00 | LPAR3 (0.41) | LPAR3LPAR2SIRT2FDPSGGPS1 | |
| Phosphoric Acid SCHEMBL4950983 | 1.00 | LPAR3 (0.41) | LPAR3LPAR2SIRT2FDPSGGPS1 | |
| Phosphoric Acid SCHEMBL4947588 | 1.00 | LPAR3 (0.41) | LPAR3LPAR2SIRT2FDPSGGPS1 | |
| Phosphoric Acid SCHEMBL4950765 | 1.00 | LPAR3 (0.41) | LPAR3LPAR2SIRT2FDPSGGPS1 | |
| Phosphoric Acid SCHEMBL4950281 | 1.00 | LPAR3 (0.41) | LPAR3LPAR2SIRT2FDPSGGPS1 | |
| Phosphoric Acid SCHEMBL4950211 | 1.00 | LPAR3 (0.41) | LPAR3LPAR2SIRT2FDPSGGPS1 | |
| Phosphoric Acid SCHEMBL4950050 | 1.00 | LPAR3 (0.41) | LPAR3LPAR2SIRT2FDPSGGPS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7432253-B2 | Phosphoepoxides, method for making same and uses | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (FR) | 2008-10-07 | — | — | US | disclosed |
| US-20060287274-A1 | Phosphoepoxides, method for making same and uses | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (FR) | 2006-12-21 | — | — | US | disclosed |
| US-7101711-B1 | Phosphoepoxides, method for making same and uses | INSTITUT NATIONAL DE LA SANTA ET DE LA RECHERCHE MEDICALE (FR) | 2006-09-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060287274-A1 | Phosphoepoxides, method for making same and uses | CD4, CCR9, BCL9 | LPAR3 868/4885LPAR2 749/4885SIRT2 4535/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.