Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.31 |
| ▸ | FEN1 | P39748 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7413262 | 0.78 | CES2 (0.43) | CES2CES1ALDH1A1 | |
| SCHEMBL8880417 | 0.71 | CES2 (0.43) | CES2CES1ALDH1A1 | |
| SCHEMBL6525908 | 0.70 | CES2 (0.42) | CES2CES1ALDH1A1 | |
| SCHEMBL2974322 | 0.66 | CES2 (0.39) | CES2CES1 | |
| SCHEMBL10608232 | 0.66 | CES1 (0.38) | CES2CES1ALDH1A1 | |
| SCHEMBL2340405 | 0.66 | CES2 (0.35) | CES2CES1ALDH1A1 | |
| SCHEMBL6940594 | 0.66 | HDAC4 (0.45) | ALDH1A1 | |
| SCHEMBL29009844 | 0.65 | CES2 (0.41) | CES2CES1ALDH1A1 | |
| SCHEMBL3691325 | 0.65 | CES2 (0.37) | CES2CES1ALDH1A1ERCC5FEN1 | |
| SCHEMBL206670 | 0.64 | CES2 (0.41) | CES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120277342-A1 | METHACRYLATE-BASED BULKY SIDE-CHAIN SILOXANE CROSS LINKERS FOR OPTICAL MEDICAL DEVICES | MCGEE JOSEPH A (US) | 2012-11-01 | — | — | US | disclosed |
| US-7344731-B2 | Rigid gas permeable lens material | BAUSCH & LOMB INCORPORATED (US) | 2008-03-18 | — | — | US | disclosed |
| US-20060276605-A1 | Rigid gas permeable lens material | BAUSCH & LOMB INCORPORATED | 2006-12-07 | — | — | US | disclosed |