Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.51 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | MITF | O75030 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | GSK3B | P49841 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL91608 | 0.84 | MAOB (0.54) | MAOBKMT2AMEN1RAB9AHDAC1 | |
| SCHEMBL5684527 | 0.83 | MAOB (0.53) | MAOBKMT2AMEN1RAB9ANR4A2 | |
| SCHEMBL92369 | 0.82 | RAB9A (0.64) | MAOBKMT2AMEN1RAB9AHDAC1 | |
| SCHEMBL91603 | 0.81 | MAOB (0.51) | MAOBKMT2AMEN1RAB9ANR4A2 | |
| SCHEMBL4811502 | 0.81 | MAOB (0.84) | MAOBKMT2AMEN1RAB9ANR4A2 | |
| SCHEMBL28749578 | 0.80 | MAOB (0.50) | MAOBKMT2AMEN1RAB9ANR4A2 | |
| SCHEMBL71040 | 0.79 | ITGB1 (0.57) | MAOBKMT2AHDAC1HDAC6NR4A2 | |
| SCHEMBL27596557 | 0.79 | ITGB1 (0.52) | MAOBKMT2AMEN1RAB9AHDAC1 | |
| SCHEMBL12861707 | 0.78 | MAOB (0.48) | MAOBKMT2AMEN1HDAC1HDAC6 | |
| SCHEMBL12861701 | 0.78 | HDAC1 (0.48) | MAOBKMT2AHDAC1HDAC6ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1961750-B1 | VLA-4 INHIBITORY DRUG | DAIICHI SANKYO CO LTD (JP) | 2013-09-18 | — | — | EP | disclosed |
| EP-1961750-A1 | VLA-4 INHIBITORY DRUG | Daiichi Sankyo Company, Limited (JP) | 2008-08-27 | — | — | EP | disclosed |