Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NT5E | P21589 | 1/20 | 0.65 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | THRB | P10828 | 1/20 | 0.62 |
| ▸ | MTOR | P42345 | 1/20 | 0.62 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.62 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.62 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | ST6GAL1 | P15907 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.44 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.44 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4414290 | 0.88 | NT5E (0.67) | NT5ELMNATHRBMTORMDM2 | |
| SCHEMBL7539957 | 0.87 | NT5E (0.65) | NT5ELMNATHRBMTORMDM2 | |
| SCHEMBL800348 | 0.87 | NT5E (0.65) | NT5ELMNATHRBMTORMDM2 | |
| SCHEMBL800434 | 0.87 | NT5E (0.65) | NT5ELMNATHRBMTORMDM2 | |
| SCHEMBL223209 | 0.87 | NT5E (0.65) | NT5ELMNATHRBMTORMDM2 | |
| SCHEMBL6312068 | 0.87 | NT5E (0.65) | NT5ELMNATHRBMTORMDM2 | |
| SCHEMBL13134657 | 0.87 | NT5E (0.65) | NT5ELMNATHRBMTORMDM2 | |
| SCHEMBL800395 | 0.87 | NT5E (0.65) | NT5ELMNATHRBMTORMDM2 | |
| SCHEMBL13190277 | 0.87 | NT5E (0.65) | NT5ELMNATHRBMTORMDM2 | |
| SCHEMBL4296424 | 0.87 | NT5E (0.65) | NT5ELMNATHRBMTORMDM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4101888-B2 | — | — | 2008-06-18 | — | — | JP | claimed |
| US-20040092468-A1 | Immunostimulatory oligonucleotides with modified bases and methods of use thereof | SCHWARTZ DAVID (US) | 2004-05-13 | — | — | US | claimed |
| US-20040006034-A1 | Immunostimulatory oligonucleotides, compositions thereof and methods of use thereof | RAZ EYAL (US) | 2004-01-08 | — | — | US | claimed |
| JP-2002517156-A | — | — | 2002-06-11 | — | — | JP | claimed |
| EP-1121373-A2 | IMMUNOSTIMULATORY OLIGONUCLEOTIDES WITH MODIFIED BASES AND METHODS OF USE THEREOF | Dynavax Technologies Corporation (US) | 2001-08-08 | — | — | EP | claimed |
| EP-0986572-A2 | IMMUNOSTIMULATORY OLIGONUCLEOTIDES, COMPOSITIONS THEREOF AND METHODS OF USE THEREOF | Dynavax Technologies Corporation (US) | 2000-03-22 | — | — | EP | claimed |
| WO-1999062923-A2 | IMMUNOSTIMULATORY OLIGONUCLEOTIDES WITH MODIFIED BASES AND METHODS OF USE THEREOF | DYNAVAX TECHNOLOGIES CORPORATION (US) | 1999-12-09 | — | — | WO | claimed |
| WO-1998055495-B1 | IMMUNOSTIMULATORY OLIGONUCLEOTIDES, COMPOSITIONS THEREOF AND METHODS OF USE THEREOF | DYNAVAX TECH CORP (US) | 1999-07-22 | — | — | WO | claimed |
| WO-1998055495-A2 | IMMUNOSTIMULATORY OLIGONUCLEOTIDES, COMPOSITIONS THEREOF AND METHODS OF USE THEREOF | DYNAVAX TECHNOLOGIES CORPORATION (US) | 1998-12-10 | — | — | WO | claimed |
| US-20070027098-A1 | Immunostimulatory oligonucleotides, compositions thereof and methods of use thereof | DYNAVAX TECHNOLOGIES CORPORATION | 2007-02-01 | — | — | US | disclosed |
| US-20040006034-A1 | Immunostimulatory oligonucleotides, compositions thereof and methods of use thereof | RAZ EYAL (US) | 2004-01-08 | — | — | US | disclosed |
| EP-1374894-A2 | Immunostimulatory oligonucleotides, compositions thereof and methods of use thereof | Dynavax Technologies Corporation (US) | 2004-01-02 | — | — | EP | disclosed |
| US-6589940-B1 | Immunostimulatory oligonucleotide compositions. These oligonucleotides comprise an immunostimulatory octanucleotide sequence. These oligonucleotides can be administered in conjunction with an immunostimulatory peptide or antigen. | DYNAVAX TECHNOLOGIES CORPORATION | 2003-07-08 | — | — | US | disclosed |
| US-20030039976-A1 | Methods for base counting | PE CORPORATION (NY) | 2003-02-27 | — | — | US | disclosed |
| EP-0986572-A2 | IMMUNOSTIMULATORY OLIGONUCLEOTIDES, COMPOSITIONS THEREOF AND METHODS OF USE THEREOF | Dynavax Technologies Corporation (US) | 2000-03-22 | — | — | EP | disclosed |
| WO-1998055495-A2 | IMMUNOSTIMULATORY OLIGONUCLEOTIDES, COMPOSITIONS THEREOF AND METHODS OF USE THEREOF | DYNAVAX TECHNOLOGIES CORPORATION (US) | 1998-12-10 | — | — | WO | disclosed |