Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 16/20 | 0.64 |
| ▸ | CSF1R | P07333 | 3/20 | 0.52 |
| ▸ | EGFR | P00533 | 1/20 | 0.51 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4952401 | 0.92 | PDE4B (0.75) | PDE4BCSF1R | |
| SCHEMBL4952294 | 0.91 | PDE4B (0.66) | PDE4BCSF1R | |
| SCHEMBL4947650 | 0.90 | PDE4B (0.75) | PDE4B | |
| SCHEMBL2475832 | 0.86 | PDE4B (0.85) | PDE4BCSF1R | |
| SCHEMBL4948607 | 0.86 | PDE4B (0.68) | PDE4B | |
| SCHEMBL4948174 | 0.86 | PDE4B (0.76) | PDE4B | |
| SCHEMBL1276218 | 0.86 | PDE4B (0.86) | PDE4B | |
| SCHEMBL4951341 | 0.84 | PDE4B (0.66) | PDE4B | |
| SCHEMBL4627512 | 0.84 | PDE4B (0.70) | PDE4B | |
| Hydrochloric Acid SCHEMBL1275850 | 0.83 | PDE4B (0.79) | PDE4BCSF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633748-B1 | QUINOLINE DERIVATIVES AS PHOSPHODIESTERASE INHIBITORS | GLAXO GROUP LTD (GB) | 2008-03-05 | — | — | EP | claimed |