Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 9/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.54 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | PGR | P06401 | 1/20 | 0.54 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.54 |
| ▸ | AR | P10275 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | DRD1 | P21728 | 1/20 | 0.54 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.54 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL69257 | 0.94 | ESR1 (0.57) | ESR1LMNASLC6A2SLC6A3CYP2C9 | |
| Ammonia Solution, Strong SCHEMBL6327541 | 0.91 | ESR1 (0.55) | ESR1LMNASLC6A2SLC6A3CYP2C9 | |
| SCHEMBL74326 | 0.89 | ESR1 (0.65) | ESR1LMNASLC6A2SLC6A3CYP2C9 | |
| SCHEMBL1171043 | 0.89 | ESR1 (0.65) | ESR1LMNASLC6A2SLC6A3CYP2C9 | |
| Hydroquinone SCHEMBL28097256 | 0.89 | ESR1 (0.65) | ESR1LMNASLC6A2SLC6A3CYP2C9 | |
| SCHEMBL1973610 | 0.88 | ESR1 (0.52) | ESR1LMNASLC6A2SLC6A3CYP2C9 | |
| Propane SCHEMBL28264453 | 0.87 | ESR1 (0.62) | ESR1LMNASLC6A2SLC6A3CYP2C9 | |
| Benzene SCHEMBL28219933 | 0.87 | ESR1 (0.62) | ESR1LMNASLC6A2SLC6A3CYP2C9 | |
| SCHEMBL28544659 | 0.87 | ESR1 (0.62) | ESR1LMNASLC6A2SLC6A3CYP2C9 | |
| SCHEMBL16504112 | 0.86 | ACHE (0.52) | ESR1LMNASLC6A2SLC6A3CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7381786-B2 | Methods of polymer preparation using polycyclic dihydroxy compounds | GENERAL ELECTRIC COMPANY (US) | 2008-06-03 | — | — | US | disclosed |
| US-20070260033-A1 | METHODS OF POLYMER PREPARATION USING POLYCYCLIC DIHYDROXY COMPOUNDS | GENERAL ELECTRIC COMPANY (US) | 2007-11-08 | — | — | US | disclosed |