Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 15/20 | 0.58 |
| ▸ | ESR2 | Q92731 | 12/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | BCL2L2 | Q92843 | 1/20 | 0.42 |
| ▸ | AR | P10275 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | PGR | P06401 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7909601 | 0.84 | ESR1 (0.63) | ESR1ESR2ALDH1A1MEN1KMT2A | |
| SCHEMBL5973519 | 0.84 | ESR1 (0.63) | ESR1ESR2ALDH1A1MEN1KMT2A | |
| SCHEMBL6562079 | 0.80 | ESR1 (0.85) | ESR1ESR2ALDH1A1ARCYP3A4 | |
| SCHEMBL30103343 | 0.79 | ESR1 (0.54) | ESR1ESR2ALDH1A1MEN1KMT2A | |
| SCHEMBL6561210 | 0.79 | ESR1 (0.75) | ESR1ESR2ALDH1A1ARCYP3A4 | |
| SCHEMBL4455629 | 0.77 | ESR1 (0.78) | ESR1ESR2AR | |
| SCHEMBL15987572 | 0.77 | ESR1 (0.72) | ESR1ESR2ALDH1A1CYP3A4LMNA | |
| SCHEMBL9847877 | 0.77 | ESR1 (0.58) | ESR1ESR2ALDH1A1ARCYP3A4 | |
| SCHEMBL335067 | 0.76 | ESR1 (0.50) | ESR1ESR2ALDH1A1ARCYP3A4 | |
| SCHEMBL1334149 | 0.76 | ESR1 (0.83) | ESR1ESR2ARCYP3A4LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7381786-B2 | Methods of polymer preparation using polycyclic dihydroxy compounds | GENERAL ELECTRIC COMPANY (US) | 2008-06-03 | — | — | US | disclosed |
| US-20070260033-A1 | METHODS OF POLYMER PREPARATION USING POLYCYCLIC DIHYDROXY COMPOUNDS | GENERAL ELECTRIC COMPANY (US) | 2007-11-08 | — | — | US | disclosed |