Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO2 | P16083 | 13/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | TOP1 | P11387 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | CASP7 | P55210 | 1/20 | 0.41 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | TOP2A | P11388 | 1/20 | 0.40 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | PRNP | P04156 | 1/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
| ▸ | TMPRSS15 | P98073 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3508130 | 0.86 | NQO2 (0.52) | NQO2ALDH1A1HPGDHSD17B10TOP1 | |
| SCHEMBL13167117 | 0.86 | KDM4E (0.49) | NQO2ALDH1A1HPGDHSD17B10TOP1 | |
| SCHEMBL5492386 | 0.84 | PRMT1 (0.51) | NQO2ALDH1A1HPGDHSD17B10TOP1 | |
| SCHEMBL5492376 | 0.74 | PRMT1 (0.55) | NQO2ALDH1A1HPGDHSD17B10TOP1 | |
| SCHEMBL5492362 | 0.74 | NQO2 (0.47) | NQO2ALDH1A1HPGDHSD17B10TOP1 | |
| SCHEMBL4946899 | 0.73 | NQO2 (0.47) | NQO2ALDH1A1HPGDHSD17B10TOP1 | |
| SCHEMBL4951247 | 0.73 | NQO2 (0.47) | NQO2ALDH1A1HPGDHSD17B10TOP1 | |
| Pafuramidine SCHEMBL5143735 | 0.72 | NQO2 (0.57) | NQO2ALDH1A1HPGDHSD17B10TOP1 | |
| SCHEMBL3504227 | 0.72 | NQO2 (0.57) | NQO2ALDH1A1HPGDHSD17B10TOP1 | |
| Acetic Acid SCHEMBL3506391 | 0.71 | NQO2 (0.82) | NQO2ALDH1A1HPGDHSD17B10TOP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1726589-B1 | 5,5'-bis-(4-amidinophenyl)-2,2'-bifuran derivatives and related compounds as antiprotozoal agent and prodrugs thereof | UNIV NORTH CAROLINA (US) | 2008-10-15 | — | — | EP | claimed |