Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 6/20 | 0.54 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | IDO1 | P14902 | 2/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.41 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | MGAM | O43451 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | SI | P14410 | 1/20 | 0.38 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.38 |
| ▸ | GPR52 | Q9Y2T5 | 2/20 | 0.38 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.38 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5286289 | 0.86 | TAAR1 (0.58) | TAAR1HTR2AIDO1FFAR1FFAR4 | |
| SCHEMBL30364680 | 0.86 | TAAR1 (0.58) | TAAR1HTR2AIDO1FFAR1FFAR4 | |
| SCHEMBL6738136 | 0.83 | TAAR1 (0.71) | TAAR1IDO1GPR52 | |
| SCHEMBL29351396 | 0.83 | TAAR1 (0.71) | TAAR1IDO1GPR52 | |
| SCHEMBL11781929 | 0.81 | TAAR1 (0.45) | TAAR1HTR2AFFAR1FFAR4CXCR3 | |
| SCHEMBL2099265 | 0.79 | TAAR1 (0.50) | TAAR1HTR2AIDO1FFAR1FFAR4 | |
| SCHEMBL11780254 | 0.79 | TAAR1 (0.65) | TAAR1HTR2AIDO1 | |
| SCHEMBL11782450 | 0.79 | TAAR1 (0.43) | TAAR1HTR2AFFAR1FFAR4GPR52 | |
| SCHEMBL11780482 | 0.79 | TAAR1 (0.54) | TAAR1HTR2AIDO1CXCR3GPR52 | |
| SCHEMBL1772877 | 0.79 | TAAR1 (0.56) | TAAR1HTR2AFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7449539-B2 | Silsesquioxane derivative and production process for the same | CHISSO CORPORATION (JP) | 2008-11-11 | — | — | US | disclosed |