Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.58 |
| ▸ | HTR1A | P08908 | 1/20 | 0.48 |
| ▸ | DRD2 | P14416 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | IDO1 | P14902 | 2/20 | 0.45 |
| ▸ | MAOA | P21397 | 2/20 | 0.44 |
| ▸ | MAOB | P27338 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.44 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.43 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.43 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.43 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30364680 | 1.00 | TAAR1 (0.58) | TAAR1HTR1ADRD2TDP1IDO1 | |
| SCHEMBL29351396 | 0.87 | TAAR1 (0.71) | TAAR1IDO1ALDH1A1HSD17B10GPR52 | |
| SCHEMBL6738136 | 0.87 | TAAR1 (0.71) | TAAR1IDO1ALDH1A1HSD17B10GPR52 | |
| SCHEMBL4946934 | 0.86 | TAAR1 (0.54) | TAAR1IDO1FFAR1FFAR4GPR52 | |
| SCHEMBL29809460 | 0.86 | TAAR1 (0.54) | TAAR1TDP1IDO1MAOAMAOB | |
| SCHEMBL55137 | 0.82 | HTR1A (0.58) | TAAR1HTR1ADRD2TDP1MAOA | |
| SCHEMBL8406787 | 0.81 | HTR1A (0.46) | HTR1ADRD2TDP1ALDH1A1 | |
| SCHEMBL8409879 | 0.80 | HTR1A (0.44) | TAAR1HTR1ADRD2TDP1IDO1 | |
| SCHEMBL423302 | 0.78 | HTR2A (0.56) | TAAR1IDO1HPGDHTR2ASMN1; SMN2 | |
| Benzene SCHEMBL28195073 | 0.78 | HTR2A (0.56) | TAAR1IDO1HPGDHTR2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180090694-A1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2018-03-29 | — | — | US | disclosed |
| US-20180090694-A1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2018-03-29 | — | — | US | disclosed |
| US-9847499-B2 | Metal complexes | MERCK PATENT GMBH (DE) | 2017-12-19 | — | — | US | disclosed |
| US-9847499-B2 | Metal complexes | MERCK PATENT GMBH (DE) | 2017-12-19 | — | — | US | disclosed |
| EP-2742054-B1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2016-10-12 | — | — | EP | disclosed |
| CN-103242128-B | Preparation method of 9,10-dihydrophenanthrene derivatives | UNIV SOOCHOW | 2015-02-18 | — | — | CN | disclosed |
| US-8883816-B2 | Fused and spirocycle compounds and the use thereof | PURDUE PHARMA L.P. (US) | 2014-11-11 | — | — | US | disclosed |
| US-20140183422-A1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2014-07-03 | — | — | US | disclosed |
| US-20140183422-A1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2014-07-03 | — | — | US | disclosed |
| US-20140045875-A1 | Fused and Spirocycle Compounds and the Use Thereof | PURDUE PHARMA L.P. (US) | 2014-02-13 | — | — | US | disclosed |
| EP-0178826-B2 | Fungicides | SYNGENTA LTD (GB) | 2003-04-09 | — | — | EP | disclosed |
| CN-1377375-A | Methanol extraction polar organic compounds and modifier compounds from poly (arylene sulfide) polymer and oligomer streams | PHILLIPS PETROLEUM CO (US) | 2002-10-30 | — | — | CN | disclosed |
| CN-1377376-A | Recovery of modifier compounds and polar organic compounds from a poly (arylene sulfide) | PHILLIPS PETROLEUM CO (US) | 2002-10-30 | — | — | CN | disclosed |
| US-5315025-A | Acrylate ethers | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1994-05-24 | — | — | US | disclosed |
| US-5286894-A | Phenyl acrylic acid derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1994-02-15 | — | — | US | disclosed |
| EP-0178826-B1 | FUNGICIDES | ZENECA LIMITED (GB) | 1991-12-18 | — | — | EP | disclosed |
| EP-0431328-A2 | Fungicides | ZENECA LIMITED (GB) | 1991-06-12 | — | — | EP | disclosed |
| EP-0178826-A2 | Fungicides | ZENECA LIMITED (GB) | 1986-04-23 | — | — | EP | disclosed |
| US-4071570-A | ANTIARRHYTHMIC AGENTS | MERCK & CO., INC. (US) | 1978-01-31 | — | — | US | disclosed |
| US-3978127-A | ANTIARRHYTHMIC | MERCK & CO., INC. (US) | 1976-08-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180090694-A1 | METAL COMPLEXES | AP3M1, AP2M1, AP1M1 | TAAR1 2452/4885HTR1A 4665/4885DRD2 2191/4885 |
| US-20140045875-A1 | Fused and Spirocycle Compounds and the Use Thereof | CACNA1A, CACNA1E, CACNA1C | TAAR1 1029/4885HTR1A 2015/4885DRD2 639/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.