Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CIT | O14578 | 6/20 | 0.41 |
| ▸ | DYRK3 | O43781 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | AAK1 | Q2M2I8 | 7/20 | 0.38 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.37 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.37 |
| ▸ | PIM1 | P11309 | 1/20 | 0.37 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.37 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.37 |
| ▸ | CLK1 | P49759 | 1/20 | 0.37 |
| ▸ | CLK3 | P49761 | 1/20 | 0.37 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.37 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.37 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.37 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.37 |
| ▸ | MYLK2 | Q9H1R3 | 1/20 | 0.37 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.37 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4944544 | 0.92 | DYRK3 (0.41) | DYRK3ALDH1A1CISD1PIK3CDPIM1 | |
| SCHEMBL2996481 | 0.90 | DYRK3 (0.42) | DYRK3ALDH1A1CISD1PIK3CDPIM1 | |
| SCHEMBL2996479 | 0.90 | DYRK3 (0.42) | DYRK3ALDH1A1CISD1PIK3CDPIM1 | |
| SCHEMBL2999961 | 0.89 | CDK1 (0.44) | CITDYRK3ALDH1A1CISD1PIK3CD | |
| SCHEMBL2999956 | 0.89 | CDK1 (0.44) | CITDYRK3ALDH1A1CISD1PIK3CD | |
| SCHEMBL2993505 | 0.88 | ALDH1A1 (0.40) | DYRK3ALDH1A1CISD1PIK3CDPIM1 | |
| SCHEMBL2993503 | 0.88 | ALDH1A1 (0.40) | DYRK3ALDH1A1CISD1PIK3CDPIM1 | |
| SCHEMBL2997008 | 0.88 | DYRK3 (0.41) | DYRK3ALDH1A1CISD1PIK3CDPIM1 | |
| SCHEMBL2997009 | 0.88 | DYRK3 (0.41) | DYRK3ALDH1A1CISD1PIK3CDPIM1 | |
| SCHEMBL2993877 | 0.86 | NPC1 (0.41) | DYRK3CISD1PIK3CDPIM1CSNK2A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1885362-A2 | NOVEL CHEMICAL COMPOUNDS | Smithkline Beecham Corporation (US) | 2008-02-13 | — | — | EP | claimed |
| WO-2006127458-A2 | NOVEL CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2006-11-30 | — | — | WO | claimed |