Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD | O00767 | 3/20 | 0.41 |
| ▸ | DRD2 | P14416 | 3/20 | 0.39 |
| ▸ | DRD4 | P21917 | 3/20 | 0.39 |
| ▸ | DRD3 | P35462 | 3/20 | 0.39 |
| ▸ | CCR5 | P51681 | 1/20 | 0.36 |
| ▸ | SMYD3 | Q9H7B4 | 2/20 | 0.36 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.35 |
| ▸ | PSMB9 | P28065 | 1/20 | 0.35 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.35 |
| ▸ | PDE2A | O00408 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3989771 | 0.83 | SCD (0.44) | SCDDRD2DRD4DRD3CCR5 | |
| SCHEMBL4149188 | 0.79 | SCD (0.44) | SCDDRD2DRD4DRD3SMYD3 | |
| SCHEMBL3990440 | 0.79 | SCD (0.50) | SCDDRD2DRD4DRD3SMYD3 | |
| SCHEMBL3984724 | 0.79 | DRD2 (0.51) | SCDDRD2DRD4DRD3ACHE | |
| SCHEMBL3989997 | 0.77 | SCD (0.48) | SCDDRD2DRD4DRD3SMYD3 | |
| SCHEMBL21317604 | 0.75 | PSMB8 (0.50) | SCDSMYD3PSMB8PSMB9PSMB5 | |
| SCHEMBL30489440 | 0.75 | PSMB8 (0.50) | SCDSMYD3PSMB8PSMB9PSMB5 | |
| SCHEMBL3983823 | 0.75 | SCD (0.55) | SCDACHESCD5 | |
| SCHEMBL3981678 | 0.73 | HRH4 (0.41) | SCDSMYD3PSMB8PSMB9PSMB5 | |
| SCHEMBL4949165 | 0.68 | SMN1; SMN2 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1893572-A2 | FACTOR XA INHIBITORS | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2008-03-05 | — | — | EP | claimed |
| WO-2006002099-A2 | FACTOR XA INHIBITORS | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2006-01-05 | — | — | WO | claimed |
| EP-1893572-A2 | FACTOR XA INHIBITORS | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2008-03-05 | — | — | EP | disclosed |
| WO-2006002099-A2 | FACTOR XA INHIBITORS | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2006-01-05 | — | — | WO | disclosed |