Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.34 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.34 |
| ▸ | F10 | P00742 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.32 |
| ▸ | XDH | P47989 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3985640 | 0.82 | ALDH1A1 (0.45) | ALDH1A1HPGDTSHRCYP1A2RAB9A | |
| SCHEMBL3985648 | 0.82 | F10 (0.46) | ALDH1A1HPGDTSHRF10RAB9A | |
| SCHEMBL3984017 | 0.71 | F10 (0.45) | ALDH1A1F10CYP1A2PTGS2RAB9A | |
| SCHEMBL3984020 | 0.71 | F10 (0.59) | F10PTGS2RAB9A | |
| SCHEMBL85673 | 0.71 | ALDH1A1 (0.50) | ALDH1A1HPGDTSHRF10PTGS2 | |
| SCHEMBL1096482 | 0.71 | F10 (0.59) | F10 | |
| SCHEMBL3983909 | 0.68 | ALDH1A1 (0.48) | ALDH1A1HPGDTSHRCYP1A2RAB9A | |
| SCHEMBL3983914 | 0.68 | ALDH1A1 (0.42) | ALDH1A1HPGDTSHRF10 | |
| SCHEMBL3982913 | 0.68 | F10 (0.40) | ALDH1A1HPGDTSHRF10 | |
| SCHEMBL3982910 | 0.68 | NPC1 (0.48) | ALDH1A1HPGDTSHRRAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1893572-A2 | FACTOR XA INHIBITORS | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2008-03-05 | — | — | EP | claimed |
| WO-2006002099-A2 | FACTOR XA INHIBITORS | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2006-01-05 | — | — | WO | claimed |