Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 13/20 | 0.70 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.39 |
| ▸ | FABP3 | P05413 | 1/20 | 0.37 |
| ▸ | FABP4 | P15090 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | JAK1 | P23458 | 1/20 | 0.35 |
| ▸ | TYK2 | P29597 | 1/20 | 0.35 |
| ▸ | JAK3 | P52333 | 1/20 | 0.35 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.34 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1275581 | 0.82 | PDE4B (1.00) | PDE4B | |
| SCHEMBL5069811 | 0.76 | PDE4B (0.53) | PDE4BMTNR1BMAPTP2RX7 | |
| SCHEMBL2478763 | 0.75 | PDE4B (0.74) | PDE4B | |
| SCHEMBL1275589 | 0.74 | PDE4B (0.75) | PDE4B | |
| SCHEMBL1276433 | 0.74 | PDE4B (0.81) | PDE4B | |
| Hydrochloric Acid SCHEMBL2481486 | 0.73 | PDE4B (0.74) | PDE4B | |
| SCHEMBL4627075 | 0.73 | PDE4B (0.82) | PDE4B | |
| SCHEMBL4627565 | 0.72 | PDE4B (0.79) | PDE4B | |
| SCHEMBL1275366 | 0.72 | PDE4B (0.74) | PDE4B | |
| SCHEMBL2484127 | 0.71 | PDE4B (0.73) | PDE4BMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633748-B1 | QUINOLINE DERIVATIVES AS PHOSPHODIESTERASE INHIBITORS | GLAXO GROUP LTD (GB) | 2008-03-05 | — | — | EP | claimed |