Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 3/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.34 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.34 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 2/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4952600 | 0.82 | TAAR1 (0.32) | KCNN4MAPK1TAAR1CYP2C19HIF1A | |
| SCHEMBL4952329 | 0.78 | KCNN4 (0.34) | KCNN4MAPK1ALDH1A1TSHR | |
| SCHEMBL4947666 | 0.78 | KCNN4 (0.34) | KCNN4MAPK1ALDH1A1TSHR | |
| SCHEMBL4949811 | 0.77 | KCNN4 (0.33) | KCNN4ALDH1A1TSHR | |
| SCHEMBL4950368 | 0.76 | TAAR1 (0.33) | KCNN4MAPK1TAAR1HDAC3HDAC4 | |
| SCHEMBL21647231 | 0.74 | ALDH1A1 (0.50) | KCNN4MAPK1ALDH1A1TAAR1ALOX15 | |
| SCHEMBL4952285 | 0.72 | KCNN4 (0.33) | KCNN4ALDH1A1TSHR | |
| SCHEMBL4813303 | 0.70 | KCNN4 (0.38) | KCNN4MAPK1ALDH1A1TAAR1ALOX15 | |
| SCHEMBL15064283 | 0.70 | ALDH1A1 (0.38) | KCNN4MAPK1ALDH1A1TAAR1ALOX15 | |
| SCHEMBL4951626 | 0.70 | KCNN4 (0.39) | KCNN4MAPK1ALDH1A1TAAR1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7378449-B2 | Poly(bromoaryl)alkane additives and methods for their preparation and use | ALBEMARLE CORPORATION (US) | 2008-05-27 | — | — | US | disclosed |
| US-20070093582-A1 | POLY(BROMOARYL)ALKANE ADDITIVES AND METHODS FOR THEIR PREPARATION AND USE | ALBEMARLE CORPORATION (US) | 2007-04-26 | — | — | US | disclosed |
| US-7129385-B2 | Poly(bromoaryl)alkane additives and methods for their preparation and use | ALBEMARLE CORPORATION (US) | 2006-10-31 | — | — | US | disclosed |
| US-20040195087-A1 | Poly(bromoaryl)alkane additives and methods for their preparation and use | ALBEMARLE CORPORATION | 2004-10-07 | — | — | US | disclosed |
| US-6743825-B1 | Poly(bromoaryl)alkane additives and methods for their preparation and use | ALBEMARLE CORPORATION | 2004-06-01 | — | — | US | disclosed |