Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 6/20 | 0.47 |
| ▸ | AKR1C2 | P52895 | 6/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | FABP2 | P12104 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.47 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.47 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.47 |
| ▸ | HTR2C | P28335 | 1/20 | 0.47 |
| ▸ | DRD3 | P35462 | 1/20 | 0.47 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.47 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8602846 | 0.84 | CA12 (0.42) | MEN1KMT2APTGS2MAPTHPGD | |
| SCHEMBL8465277 | 0.81 | MAOB (0.41) | LMNAPTGS2MAPTADRA2BHPGD | |
| SCHEMBL28535158 | 0.80 | AKR1C3 (0.65) | AKR1C3AKR1C2PTGS1LMNAMEN1 | |
| SCHEMBL4949023 | 0.79 | AKR1C3 (0.63) | AKR1C3AKR1C2PTGS1LMNAMEN1 | |
| SCHEMBL2918748 | 0.79 | AKR1C3 (0.63) | AKR1C3AKR1C2PTGS1LMNAMEN1 | |
| SCHEMBL7348404 | 0.79 | AKR1C3 (0.63) | AKR1C3AKR1C2PTGS1LMNAMEN1 | |
| SCHEMBL2474403 | 0.74 | PDE3B (0.45) | AKR1C3AKR1C2PTGS1LMNAMEN1 | |
| SCHEMBL17951222 | 0.74 | PTPRC (0.58) | AKR1C3AKR1C2PTGS1LMNAMEN1 | |
| SCHEMBL7167173 | 0.72 | GRIA4 (0.51) | AKR1C3AKR1C2PTGS1LMNAMEN1 | |
| SCHEMBL19308531 | 0.72 | FEN1 (0.50) | AKR1C3AKR1C2PTGS1LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008074717-A2 | PROCESS FOR THE PREPARATION OF CHIRAL 2-ARYLPROPANOLS HAVING A PROFEN-LIKE SUBSTITUTED ARYL RESIDUE | ALMA MATER STUDIORUM - UNIVERSITA DI BOLOGNA (IT) | 2008-06-26 | — | — | WO | disclosed |