Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 13/20 | 0.71 |
| ▸ | GSK3A | P49840 | 6/20 | 0.43 |
| ▸ | SCARB1 | Q8WTV0 | 3/20 | 0.43 |
| ▸ | SRC | P12931 | 4/20 | 0.41 |
| ▸ | SYK | P43405 | 3/20 | 0.41 |
| ▸ | LCK | P06239 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4947294 | 0.93 | MAPK14 (0.73) | MAPK14GSK3ASCARB1SRCSYK | |
| SCHEMBL4948532 | 0.92 | MAPK14 (0.73) | MAPK14GSK3ASCARB1SRCSYK | |
| SCHEMBL4943717 | 0.86 | MAPK14 (0.65) | MAPK14GSK3ASCARB1SRC | |
| SCHEMBL4949392 | 0.86 | MAPK14 (0.52) | MAPK14GSK3ASCARB1SRCSYK | |
| SCHEMBL4948529 | 0.85 | MAPK14 (0.82) | MAPK14GSK3ASCARB1 | |
| SCHEMBL4948867 | 0.83 | MAPK14 (0.72) | MAPK14GSK3ASCARB1 | |
| SCHEMBL14155409 | 0.81 | MAPK14 (0.59) | MAPK14GSK3ASCARB1SRCSYK | |
| SCHEMBL4955593 | 0.78 | MAPK14 (0.51) | MAPK14GSK3ASCARB1SRCSYK | |
| SCHEMBL5314960 | 0.78 | MAPK14 (0.65) | MAPK14GSK3ASCARB1SRCSYK | |
| SCHEMBL12669854 | 0.78 | MAPK14 (0.67) | MAPK14GSK3ASCARB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008089034-A2 | CYTOKINE INHIBITORS | KEMIA, INC. (US) | 2008-07-24 | — | — | WO | disclosed |