Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | LPAR1 | Q92633 | 3/20 | 0.42 |
| ▸ | LPAR2 | Q9HBW0 | 3/20 | 0.42 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 6/20 | 0.42 |
| ▸ | S1PR3 | Q99500 | 6/20 | 0.42 |
| ▸ | S1PR2 | O95136 | 5/20 | 0.42 |
| ▸ | S1PR5 | Q9H228 | 4/20 | 0.42 |
| ▸ | PGD | P52209 | 1/20 | 0.40 |
| ▸ | LPAR3 | Q9UBY5 | 5/20 | 0.38 |
| ▸ | PGK1 | P00558 | 1/20 | 0.37 |
| ▸ | PGK2 | P07205 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1399083 | 1.00 | MEN1 (0.61) | MEN1KMT2ALPAR1LPAR2ENPP2 | |
| SCHEMBL13199295 | 0.82 | LPAR1 (0.43) | MEN1KMT2ALPAR1LPAR2ENPP2 | |
| SCHEMBL13924989 | 0.81 | LPAR1 (0.40) | MEN1KMT2ALPAR1LPAR2ENPP2 | |
| SCHEMBL13903932 | 0.81 | LPAR1 (0.40) | MEN1KMT2ALPAR1LPAR2ENPP2 | |
| SCHEMBL17327606 | 0.80 | MEN1 (0.70) | MEN1KMT2AUSP2TSHR | |
| SCHEMBL13985616 | 0.80 | LPAR1 (0.42) | MEN1KMT2ALPAR1LPAR2ENPP2 | |
| SCHEMBL15705547 | 0.77 | PTGS1 (0.58) | LPAR1LPAR2ENPP2S1PR1S1PR3 | |
| SCHEMBL17753845 | 0.76 | LPAR1 (0.46) | LPAR1LPAR2ENPP2LPAR3USP2 | |
| SCHEMBL13446146 | 0.75 | S1PR1 (0.40) | MEN1KMT2ALPAR1LPAR2ENPP2 | |
| SCHEMBL8533026 | 0.75 | KMT2A (0.67) | MEN1KMT2AUSP2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012054528-A2 | CHEMOSENSORY RECEPTOR LIGAND-BASED THERAPIES | ELCELYX THERAPEUTICS, INC. (US) | 2012-04-26 | — | — | WO | disclosed |