SCHEMBL1399083

SCHEMBL1399083

CC(O)C(=O)NCCOP(=O)(O)O

nearest known ligand 0.61

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.61
KMT2A Q03164 1/20 0.61
LPAR1 Q92633 3/20 0.42
LPAR2 Q9HBW0 3/20 0.42
ENPP2 Q13822 1/20 0.42
S1PR1 P21453 6/20 0.42
S1PR3 Q99500 6/20 0.42
S1PR2 O95136 5/20 0.42
S1PR5 Q9H228 4/20 0.42
PGD P52209 1/20 0.40
LPAR3 Q9UBY5 5/20 0.38
PGK1 P00558 1/20 0.37
PGK2 P07205 1/20 0.37
USP2 O75604 1/20 0.36
TSHR P16473 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4949000 1.00 MEN1 (0.61) MEN1KMT2ALPAR1LPAR2ENPP2
SCHEMBL13199295 0.82 LPAR1 (0.43) MEN1KMT2ALPAR1LPAR2ENPP2
SCHEMBL13924989 0.81 LPAR1 (0.40) MEN1KMT2ALPAR1LPAR2ENPP2
SCHEMBL13903932 0.81 LPAR1 (0.40) MEN1KMT2ALPAR1LPAR2ENPP2
SCHEMBL17327606 0.80 MEN1 (0.70) MEN1KMT2AUSP2TSHR
SCHEMBL13985616 0.80 LPAR1 (0.42) MEN1KMT2ALPAR1LPAR2ENPP2
SCHEMBL15705547 0.77 PTGS1 (0.58) LPAR1LPAR2ENPP2S1PR1S1PR3
SCHEMBL17753845 0.76 LPAR1 (0.46) LPAR1LPAR2ENPP2LPAR3USP2
SCHEMBL13446146 0.75 S1PR1 (0.40) MEN1KMT2ALPAR1LPAR2ENPP2
SCHEMBL8533026 0.75 KMT2A (0.67) MEN1KMT2AUSP2TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025125392-A1 IMPROVEMENTS IN OR RELATING TO ORGANIC COMPOUNDS GIVAUDAN SA (CH) 2025-06-19 WO claimed
CN-116660543-A Diagnostic and prognostic markers for nonalcoholic fatty liver disease and uses thereof 中国人民解放军陆军军医大学第一附属医院 2023-08-29 CN claimed
EP-1758468-B1 TASTE IMPROVING SUBSTANCES GIVAUDAN NEDERLAND SERVICES BV (NL) 2011-03-02 EP claimed
WO-2025125392-A1 IMPROVEMENTS IN OR RELATING TO ORGANIC COMPOUNDS GIVAUDAN SA (CH) 2025-06-19 WO disclosed
EP-3606357-B1 FLAVOR MODIFIERS FOR MEAT ANALOG PRODUCTS GIVAUDAN SA (CH) 2024-12-04 EP disclosed
US-20240277012-A1 DUPLICATE BEVERAGE WANG JIE (US) 2024-08-22 US disclosed
US-12035733-B2 Flavor modifiers for meat analog products GIVAUDAN SA (CH) 2024-07-16 US disclosed
US-20240108040-A1 HIGH INTENSITY SWEETENERS FIRMENICH INCORPORATED (US) 2024-04-04 US disclosed
US-11758933-B2 High intensity sweeteners FIRMENICH INCORPORATED (US) 2023-09-19 US disclosed
US-20230091950-A1 Flavor Modifiers For Meat Analog Products GIVAUDAN SA (CH) 2023-03-23 US disclosed
US-11517036-B2 Flavor modifiers for meat analog products GIVAUDAN SA (CH) 2022-12-06 US disclosed
EP-3368542-B1 HIGH INTENSITY SWEETENERS FIRMENICH INCORPORATED (US) 2022-06-22 EP disclosed
US-11357246-B2 High intensity sweeteners FIRMENICH INCORPORATED (US) 2022-06-14 US disclosed
CN-111343870-A Perfume composition 奇华顿股份有限公司 2020-06-26 CN disclosed
CN-106999973-A System and method for discharging edible material 阿甘芳香和精细化工有限公司 2017-08-01 CN disclosed
EP-1758468-B1 TASTE IMPROVING SUBSTANCES GIVAUDAN NEDERLAND SERVICES BV (NL) 2011-03-02 EP disclosed
EP-1758468-A1 TASTE IMPROVING SUBSTANCES Quest International Services B.V. (NL) 2007-03-07 EP disclosed
WO-2005102071-A1 TASTE IMPROVING SUBSTANCES QUEST INTERNATIONAL SERVICES B.V. (NL) 2005-11-03 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240108040-A1 HIGH INTENSITY SWEETENERS TAS2R40, TAS2R60, TAS1R1 MEN1 2644/4885KMT2A 2697/4885LPAR1 3679/4885
US-11357246-B2 High intensity sweeteners TAS2R40, TAS2R60, TAS1R1 MEN1 2644/4885KMT2A 2697/4885LPAR1 3679/4885
US-11758933-B2 High intensity sweeteners TAS2R40, TAS2R60, TAS1R1 MEN1 2644/4885KMT2A 2697/4885LPAR1 3679/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.