Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AB1 | P08238 | 5/20 | 0.42 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 8/20 | 0.36 |
| ▸ | MAPK11 | Q15759 | 7/20 | 0.36 |
| ▸ | MAPK13 | O15264 | 6/20 | 0.36 |
| ▸ | MAPK12 | P53778 | 6/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
| ▸ | PDE2A | O00408 | 1/20 | 0.31 |
| ▸ | PDE6D | O43924 | 1/20 | 0.31 |
| ▸ | PDE6A | P16499 | 1/20 | 0.31 |
| ▸ | PDE6G | P18545 | 1/20 | 0.31 |
| ▸ | PDE6B | P35913 | 1/20 | 0.31 |
| ▸ | PDE6C | P51160 | 1/20 | 0.31 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.31 |
| ▸ | PDE6H | Q13956 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4946667 | 0.92 | PDE7A (0.38) | HSP90AB1PDE7AMAPK14MAPK11MAPK13 | |
| SCHEMBL1065138 | 0.88 | HSP90AB1 (0.43) | HSP90AB1MAPK14MAPK11MAPK13MAPK12 | |
| SCHEMBL1065530 | 0.86 | HSP90AB1 (0.43) | HSP90AB1MAPK14MAPK11MAPK13MAPK12 | |
| SCHEMBL1065155 | 0.84 | MAPK14 (0.50) | HSP90AB1PDE7AMAPK14MAPK11MAPK13 | |
| SCHEMBL4949365 | 0.84 | PDE7A (0.39) | PDE7A | |
| SCHEMBL4470039 | 0.83 | MAPK14 (0.46) | HSP90AB1MAPK14MAPK11MAPK13MAPK12 | |
| SCHEMBL1064227 | 0.83 | HSP90AB1 (0.44) | HSP90AB1MAPK14MAPK11MAPK13MAPK12 | |
| SCHEMBL1063961 | 0.83 | HSP90AB1 (0.44) | HSP90AB1PDE7AMAPK14MAPK11MAPK13 | |
| SCHEMBL1063029 | 0.79 | HSP90AB1 (0.46) | HSP90AB1MAPK14MAPK11MAPK13MAPK12 | |
| SCHEMBL14289717 | 0.79 | HSP90AB1 (0.46) | HSP90AB1MAPK14MAPK11MAPK13MAPK12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080268044-A1 | Novel Process and Formulations | GLAXO GROUP LIMITED | 2008-10-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080268044-A1 | Novel Process and Formulations | UGT1A7, UGT2B7, CYP3A7 | HSP90AB1 4596/4885PDE7A 68/4885MAPK14 2969/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.