Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.47 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.47 |
| ▸ | THPO | P40225 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | CHKA | P35790 | 3/20 | 0.41 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.40 |
| ▸ | PNP | P00491 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4949185 | 1.00 | CYP1A2 (0.47) | CYP1A2KMT2AADORA2AADORA2BTHPO | |
| SCHEMBL4948967 | 0.80 | CYP1A2 (0.49) | CYP1A2KMT2AADORA2AADORA2BTHPO | |
| SCHEMBL4948978 | 0.80 | CYP1A2 (0.49) | CYP1A2KMT2AADORA2AADORA2BTHPO | |
| SCHEMBL23897429 | 0.74 | AHCY (0.62) | ADORA2AADORA2BCHKAPNPLMNA | |
| SCHEMBL5582394 | 0.70 | AHCY (0.60) | KMT2AADORA2AADORA2BMEN1CYP2C9 | |
| SCHEMBL5582393 | 0.70 | AHCY (0.60) | KMT2AADORA2AADORA2BMEN1CYP2C9 | |
| SCHEMBL31309583 | 0.70 | AHCY (0.60) | KMT2AADORA2AADORA2BMEN1CYP2C9 | |
| SCHEMBL22992329 | 0.70 | AHCY (0.60) | KMT2AADORA2AADORA2BMEN1CYP2C9 | |
| SCHEMBL22762138 | 0.70 | AHCY (0.60) | KMT2AADORA2AADORA2BMEN1CYP2C9 | |
| SCHEMBL21967677 | 0.69 | FLT3 (0.48) | KMT2AMEN1CYP2C9BLMPDGFRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1990054-A1 | Polymerase inhibitors and their use in treating tumours | Freie Universität Berlin (DE) | 2008-11-12 | — | — | EP | disclosed |