Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 13/20 | 0.78 |
| ▸ | DDR2 | Q16832 | 1/20 | 0.66 |
| ▸ | SCARB1 | Q8WTV0 | 5/20 | 0.53 |
| ▸ | CNR1 | P21554 | 1/20 | 0.53 |
| ▸ | CNR2 | P34972 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4948810 | 0.89 | MAPK14 (0.75) | MAPK14DDR2SCARB1CNR1CNR2 | |
| SCHEMBL4949200 | 0.88 | MAPK14 (1.00) | MAPK14DDR2SCARB1CNR1CNR2 | |
| SCHEMBL14155367 | 0.86 | MAPK14 (0.72) | MAPK14DDR2SCARB1CNR1CNR2 | |
| SCHEMBL4959679 | 0.85 | MAPK14 (0.71) | MAPK14DDR2SCARB1CNR1CNR2 | |
| SCHEMBL4951826 | 0.85 | MAPK14 (0.94) | MAPK14DDR2SCARB1CNR1CNR2 | |
| SCHEMBL4955835 | 0.84 | MAPK14 (0.92) | MAPK14DDR2SCARB1CNR1CNR2 | |
| SCHEMBL4954759 | 0.82 | MAPK14 (0.73) | MAPK14SCARB1CNR1CNR2 | |
| SCHEMBL1600284 | 0.82 | MAPK14 (0.87) | MAPK14SCARB1 | |
| SCHEMBL4948561 | 0.81 | MEN1 (0.52) | MAPK14DDR2 | |
| SCHEMBL1599555 | 0.81 | MAPK14 (0.74) | MAPK14SCARB1CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008089034-A2 | CYTOKINE INHIBITORS | KEMIA, INC. (US) | 2008-07-24 | — | — | WO | disclosed |