Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 7/20 | 0.43 |
| ▸ | F2 | P00734 | 2/20 | 0.43 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.43 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.43 |
| ▸ | TMPRSS6 | Q8IU80 | 2/20 | 0.43 |
| ▸ | ST14 | Q9Y5Y6 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.40 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.40 |
| ▸ | APP | P05067 | 1/20 | 0.40 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.39 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4954456 | 1.00 | PRSS1 (0.43) | PRSS1F2PRSS2PRSS3TMPRSS6 | |
| Hydrochloric Acid SCHEMBL4953761 | 0.98 | PRSS1 (0.45) | PRSS1F2PRSS2PRSS3TMPRSS6 | |
| SCHEMBL4949075 | 0.98 | GAA (0.42) | PRSS1F2PRSS2PRSS3TMPRSS6 | |
| SCHEMBL11312557 | 0.93 | KCNH3 (0.44) | PRSS1GAAMAPTABCB11CYP3A4 | |
| SCHEMBL128126 | 0.85 | MAPT (0.47) | GAAMAPTABCB11CYP3A4ADRA2B | |
| SCHEMBL12712067 | 0.84 | PRSS1 (0.55) | PRSS1F2PRSS2PRSS3TMPRSS6 | |
| SCHEMBL18549015 | 0.84 | PRSS1 (0.55) | PRSS1F2PRSS2PRSS3TMPRSS6 | |
| SCHEMBL12736182 | 0.84 | PRSS1 (0.55) | PRSS1F2PRSS2PRSS3TMPRSS6 | |
| Hydrochloric Acid SCHEMBL9680720 | 0.83 | KCNH3 (0.49) | GAAMAPTABCB11CYP3A4ADRA2B | |
| Hydrochloric Acid SCHEMBL3337783 | 0.83 | KCNH3 (0.49) | GAAMAPTABCB11CYP3A4ADRA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1568684-A1 | para-phenylenediamines carrying an alkoxy group, dye composition, preparation methods and their use | L'OREAL (FR) | 2005-08-31 | — | — | EP | claimed |
| US-7435267-B2 | Secondary para-phenylenediamines bearing an alkoxy group, dye composition comprising them, processes therefor and uses thereof | L'OREAL S.A. (FR) | 2008-10-14 | — | — | US | disclosed |
| US-7435267-B2 | Secondary para-phenylenediamines bearing an alkoxy group, dye composition comprising them, processes therefor and uses thereof | L'OREAL S.A. (FR) | 2008-10-14 | — | — | US | disclosed |
| US-7435267-B2 | Secondary para-phenylenediamines bearing an alkoxy group, dye composition comprising them, processes therefor and uses thereof | L'OREAL S.A. (FR) | 2008-10-14 | — | — | US | disclosed |
| US-20060021158-A1 | Secondary para-phenylenediamines bearing an alkoxy group, dye composition comprising them, processes therefor and uses thereof | L'OREAL S.A. (FR) | 2006-02-02 | — | — | US | disclosed |
| EP-1568684-A1 | para-phenylenediamines carrying an alkoxy group, dye composition, preparation methods and their use | L'OREAL (FR) | 2005-08-31 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060021158-A1 | Secondary para-phenylenediamines bearing an alkoxy group, dye composition comprising them, processes therefor and uses thereof | KRT18, NOTUM, ALDH7A1 | PRSS1 904/4885F2 1885/4885PRSS2 1201/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.