SCHEMBL4949600

SCHEMBL4949600

CC(=CC(C=Cc1ccccc1)=CC#N)C(=O)O

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GLA P06280 1/20 0.49
TDP1 Q9NUW8 1/20 0.49
AKR1C3 P42330 1/20 0.45
ALDH1A1 P00352 3/20 0.43
LMNA P02545 3/20 0.43
MAPT P10636 3/20 0.43
HDAC3 O15379 2/20 0.43
HDAC4 P56524 2/20 0.43
HDAC1 Q13547 2/20 0.43
HDAC2 Q92769 2/20 0.43
HDAC8 Q9BY41 2/20 0.43
HDAC6 Q9UBN7 2/20 0.43
PLIN1 O60240 2/20 0.43
CYP2C9 P11712 2/20 0.43
RECQL P46063 2/20 0.43
PLIN5 Q00G26 2/20 0.43
ABHD5 Q8WTS1 2/20 0.43
TNKS O95271 1/20 0.43
HCAR2 Q8TDS4 1/20 0.43
HDAC7 Q8WUI4 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL301612 0.82 NPC1 (0.42) GLATDP1ALDH1A1LMNAMAPT
SCHEMBL186692 0.81 AKR1C3 (0.59) GLATDP1AKR1C3ALDH1A1LMNA
SCHEMBL8164378 0.81 TDP1 (0.42) GLATDP1ALDH1A1LMNAMAPT
SCHEMBL5409190 0.81 MAPT (0.48) GLATDP1ALDH1A1LMNAMAPT
SCHEMBL64795 0.78 HDAC3 (0.58) GLATDP1ALDH1A1LMNAMAPT
SCHEMBL4324631 0.78 HDAC3 (0.42) GLATDP1ALDH1A1LMNAMAPT
SCHEMBL7849380 0.78 GLA (0.50) GLATDP1AKR1C3ALDH1A1LMNA
Methacrylic Acid SCHEMBL1004605 0.77 GLA (0.43) GLATDP1ALDH1A1LMNAMAPT
SCHEMBL6904913 0.77 HAO1 (0.39) GLATDP1ALDH1A1LMNAMAPT
SCHEMBL364235 0.77 AKR1C3 (0.53) GLATDP1AKR1C3ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117467225-A ASA resin material and preparation method thereof 上海汽车集团股份有限公司 2024-01-30 CN claimed
CN-115403921-B Solvent-resistant high-modulus PA/ABS alloy material, and preparation method and application thereof 上海金发科技发展有限公司 2023-12-22 CN claimed
CN-115403921-A Solvent-resistant high-modulus PA/ABS alloy material and preparation method and application thereof 上海金发科技发展有限公司 2022-11-29 CN claimed
CN-109679314-B PC/ASA plastic for automotive interior parts and production process thereof 上海瀚氏科技集团有限公司 2021-02-02 CN claimed
CN-109679314-A Automotive upholstery PC/ASA plastics and its production technology 上海瀚氏科技集团有限公司 2019-04-26 CN claimed
CN-104726957-A Heat accumulation and preservation polyurethane elastic fibers containing phase change microcapsules and preparation method of heat accumulation and preservation polyurethane elastic fibers ZHEJIANG HUAFENG SPANDEX CO LTD 2015-06-24 CN claimed
CN-101787204-B Low water absorption polyamide composite and preparation method thereof SHANGHAI KUMHO SUNNY PLASTICS 2013-08-07 CN claimed
CN-101787204-A Low water absorption polyamide composite and preparation method thereof SHANGHAI KUMHO SUNNY PLASTICS 2010-07-28 CN claimed
WO-2002018479-A1 LOW IONIC CONTENT CONDUCTIVE THERMOPLASTIC MATERIALS GENERAL ELECTRIC COMPANY (US) 2002-03-07 WO claimed
US-5494718-A GLASS FIBER REINFORCED THERMOPLASTIC MATERIAL THE GEON COMPANY (US) 1996-02-27 US claimed
EP-4347711-A1 POLYMERIC COMPOSITION AND PRODUCT COMPRISING THE POLYMERIC COMPOSITION MAIP S.r.l. (IT) 2024-04-10 EP disclosed
CN-117467225-A ASA resin material and preparation method thereof 上海汽车集团股份有限公司 2024-01-30 CN disclosed
CN-115403921-B Solvent-resistant high-modulus PA/ABS alloy material, and preparation method and application thereof 上海金发科技发展有限公司 2023-12-22 CN disclosed
WO-2022254348-A1 POLYMERIC COMPOSITION AND PRODUCT COMPRISING THE POLYMERIC COMPOSITION MAIP S.R.L. (IT) 2022-12-08 WO disclosed
CN-115403921-A Solvent-resistant high-modulus PA/ABS alloy material and preparation method and application thereof 上海金发科技发展有限公司 2022-11-29 CN disclosed
US-20020143080-A1 Water based ink capable of decolorizing or discoloring and a process for the production of the same ZEBRA CO., LTD 2002-10-03 US disclosed
EP-1229089-A1 A water based ink capable of decolorizing or discoloring and a process for the production of the same ZEBRA CO., LTD. (JP) 2002-08-07 EP disclosed
WO-2002018479-A1 LOW IONIC CONTENT CONDUCTIVE THERMOPLASTIC MATERIALS GENERAL ELECTRIC COMPANY (US) 2002-03-07 WO disclosed
US-5494718-A GLASS FIBER REINFORCED THERMOPLASTIC MATERIAL THE GEON COMPANY (US) 1996-02-27 US disclosed
US-5494718-A GLASS FIBER REINFORCED THERMOPLASTIC MATERIAL THE GEON COMPANY (US) 1996-02-27 US disclosed