SCHEMBL5409190

SCHEMBL5409190

N#CC=C(C=Cc1ccccc1)C=Cc1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.48
LMNA P02545 3/20 0.48
ALDH1A1 P00352 3/20 0.48
HDAC3 O15379 2/20 0.48
HDAC4 P56524 2/20 0.48
HDAC1 Q13547 2/20 0.48
HDAC2 Q92769 2/20 0.48
HDAC8 Q9BY41 2/20 0.48
HDAC6 Q9UBN7 2/20 0.48
PLIN1 O60240 2/20 0.48
RECQL P46063 2/20 0.48
PLIN5 Q00G26 2/20 0.48
ABHD5 Q8WTS1 2/20 0.48
F3 P13726 2/20 0.48
TNKS O95271 1/20 0.48
HCAR2 Q8TDS4 1/20 0.48
HDAC7 Q8WUI4 1/20 0.48
HDAC10 Q969S8 1/20 0.48
HDAC11 Q96DB2 1/20 0.48
TNKS2 Q9H2K2 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL123981 0.93 LMNA (0.42) MAPTLMNAALDH1A1HDAC3HDAC4
SCHEMBL64795 0.89 HDAC3 (0.58) MAPTLMNAALDH1A1HDAC3HDAC4
SCHEMBL19309 0.88 LMNA (0.39) MAPTLMNAALDH1A1HDAC3HDAC4
Butadiene SCHEMBL8991739 0.87 LMNA (0.38) MAPTLMNAALDH1A1HDAC3HDAC4
Acrylonitrile SCHEMBL6375424 0.85 KDM4E (0.37) MAPTLMNAALDH1A1HDAC3HDAC4
Acrylonitrile SCHEMBL11458975 0.85 KDM4E (0.37) MAPTLMNAALDH1A1HDAC3HDAC4
Bicarbonate SCHEMBL278424 0.84 MAPT (0.43) MAPTLMNAALDH1A1HDAC3HDAC4
Vinyl Chloride SCHEMBL10482333 0.84 LMNA (0.36) MAPTLMNAALDH1A1HDAC3HDAC4
Styrene SCHEMBL7168836 0.84 ALDH1A1 (0.41) MAPTLMNAALDH1A1HDAC3HDAC4
Phosphoric Acid SCHEMBL4366545 0.83 LMNA (0.39) MAPTLMNAALDH1A1HDAC3HDAC4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1914024-B Structurally reinforced resin article and method of making the same SABIC INNOVATIVE PLASTICS IP 2011-06-29 CN claimed
JP-2007520378-A 2007-07-26 JP claimed
CN-1914024-A Structurally reinforced resin article and method of making the same GEN ELECTRIC (US) 2007-02-14 CN claimed
EP-1722958-A2 REINFORCED RESINOUS ARTICLE AND METHOD OF MAKING THE REINFORCED RESINOUS ARTICLE General Electric Company, (a New York Corporation) (US) 2006-11-22 EP claimed
WO-2005095087-A2 REINFORCED RESINOUS ARTICLE AND METHOD OF MAKING THE REINFORCED RESINOUS ARTICLE GENERAL ELECTRIC COMPANY (US) 2005-10-13 WO claimed
US-20050164023-A1 Structurally reinforced resinous article and method of making CITIBANK, N.A., AS COLLATERAL AGENT 2005-07-28 US claimed
CN-1914024-B Structurally reinforced resin article and method of making the same SABIC INNOVATIVE PLASTICS IP 2011-06-29 CN disclosed