SCHEMBL4950246

SCHEMBL4950246

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nearest known ligand 0.41

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
PYGB P11216 9/20 0.41
PYGL P06737 3/20 0.34
PYGM P11217 2/20 0.34
IGF2R P11717 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4950538 1.00 PYGB (0.41) PYGBPYGLPYGMIGF2R
SCHEMBL4951881 0.92 PYGB (0.38) PYGBPYGLPYGM
SCHEMBL4951061 0.92 PYGB (0.40) PYGBPYGLPYGM
SCHEMBL8621909 0.81 PYGB (0.46) PYGBPYGLPYGM
SCHEMBL8619177 0.81 PYGB (0.46) PYGBPYGLPYGM
SCHEMBL6931137 0.74 PYGB (0.43) PYGBPYGLPYGM
SCHEMBL7713761 0.74 PYGB (0.43) PYGBPYGLPYGM
SCHEMBL15125021 0.72 PYGB (0.48) PYGBPYGLPYGM
SCHEMBL28493519 0.72 PYGB (0.44) PYGBPYGLPYGM
SCHEMBL671123 0.72 TSHR (0.42) PYGB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080312162-A1 Methods and Compositions for Enzyme-Specific Activation of Carbohydrate-Conjugated Prodrugs THE OHIO STATE UNIVERSITY (US) 2008-12-18 US disclosed