Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | SRC | P12931 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | PGD | P52209 | 2/20 | 0.31 |
| ▸ | MMP1 | P03956 | 1/20 | 0.31 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | MMP3 | P08254 | 1/20 | 0.31 |
| ▸ | MMP9 | P14780 | 1/20 | 0.31 |
| ▸ | MMP13 | P45452 | 1/20 | 0.31 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.31 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.31 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | PDE4A | P27815 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7516069 | 0.97 | TSHR (0.47) | TSHRSRCTP53PGDMMP1 | |
| SCHEMBL27484021 | 0.83 | TP53 (0.42) | TSHRTP53MMP1MMP2MMP3 | |
| SCHEMBL7707382 | 0.82 | TSHR (0.43) | TSHRSRCTP53PGDMMP1 | |
| SCHEMBL1263842 | 0.81 | TSHR (0.47) | TSHRSRCTP53PGDMMP1 | |
| SCHEMBL7516079 | 0.81 | TSHR (0.47) | TSHRSRCTP53PGDMMP1 | |
| SCHEMBL11054851 | 0.80 | TSHR (0.48) | TSHRSRCTP53 | |
| Water SCHEMBL27193303 | 0.80 | TSHR (0.41) | TSHRSRCTP53 | |
| SCHEMBL7114338 | 0.80 | TP53 (0.44) | TSHRTP53MMP1MMP2MMP3 | |
| SCHEMBL1431069 | 0.79 | TSHR (0.45) | TSHRSRCTP53PGDMMP1 | |
| SCHEMBL28211257 | 0.77 | TP53 (0.42) | TSHRTP53MMP1MMP2MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8617605-B2 | Polymer release system | EGALET LTD. (GB) | 2013-12-31 | — | — | US | disclosed |
| US-20080254122-A1 | Polymer release system | EGALET A/S | 2008-10-16 | — | — | US | disclosed |
| US-20080234352-A1 | Controlled release solid dispersions | EGALET A/S | 2008-09-25 | — | — | US | disclosed |