Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1472352 | 0.81 | USP2 (0.32) | USP2TSHR | |
| SCHEMBL18018807 | 0.71 | MCL1 (0.34) | ALDH1A1 | |
| SCHEMBL7895328 | 0.71 | ANPEP (0.41) | USP2MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL7895324 | 0.71 | ANPEP (0.41) | USP2MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL293766 | 0.71 | — | — | |
| SCHEMBL28613679 | 0.70 | HIF1A (0.39) | — | |
| SCHEMBL8034630 | 0.70 | — | — | |
| SCHEMBL409311 | 0.68 | DPP7 (0.40) | USP2MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL20068037 | 0.67 | CRBN (0.41) | — | |
| SCHEMBL7183320 | 0.66 | ANPEP (0.47) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1993554-A2 | UROTENSIN II RECEPTOR ANTAGONISTS | Janssen Pharmaceutica, N.V. (BE) | 2008-11-26 | — | — | EP | claimed |
| WO-2007081995-A2 | UROTENSIN II RECEPTOR ANTAGONISTS | JANSSEN PHARMACEUTICA, N.V. (BE) | 2007-07-19 | — | — | WO | claimed |