Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18018807 | 0.79 | MCL1 (0.34) | DPP4 | |
| SCHEMBL20068037 | 0.78 | CRBN (0.41) | DPP4 | |
| SCHEMBL8034630 | 0.77 | — | — | |
| SCHEMBL16798170 | 0.73 | — | — | |
| SCHEMBL5675716 | 0.72 | HIF1A (0.34) | HIF1A | |
| SCHEMBL27745813 | 0.71 | — | — | |
| SCHEMBL7858435 | 0.70 | — | — | |
| SCHEMBL28513366 | 0.70 | SMN1; SMN2 (0.37) | — | |
| SCHEMBL906700 | 0.70 | — | — | |
| SCHEMBL4950272 | 0.70 | USP2 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112566910-A | Thiophene derivatives for the treatment of IgE induced diseases | UCB生物制药有限责任公司 | 2021-03-26 | — | — | CN | disclosed |