⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7495380 | 0.80 | — | — | |
| SCHEMBL10583161 | 0.79 | ALOX5 (0.42) | — | |
| SCHEMBL9729168 | 0.78 | — | — | |
| SCHEMBL467496 | 0.75 | — | — | |
| SCHEMBL1696175 | 0.74 | — | — | |
| SCHEMBL21495020 | 0.74 | — | — | |
| SCHEMBL6731353 | 0.74 | — | — | |
| SCHEMBL22774795 | 0.74 | — | — | |
| SCHEMBL5750352 | 0.74 | — | — | |
| SCHEMBL1696274 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101870700-B | Method for synthesizing Indiplon | UNIV PLA 3RD MILITARY MEDICAL | 2012-05-23 | — | — | CN | claimed |
| CN-101870700-A | Method for synthesizing Indiplon | UNIV PLA 3RD MILITARY MEDICAL | 2010-10-27 | — | — | CN | claimed |
| CN-109422765-A | C class beta-lactamase inhibitor and its preparation method and application | 香港理工大学深圳研究院 | 2019-03-05 | — | — | CN | disclosed |
| CN-105164125-B | 2-phenyl or 2-heteroaryl imidazo [1,2-a ] pyridine derivatives | 豪夫迈·罗氏有限公司 | 2017-10-13 | — | — | CN | disclosed |
| JP-2013256501-A | (E)-N-MONOALKYL-3-OXO-3-(2-THIENYL)PROPENAMINE AND METHOD FOR MANUFACTURING THE SAME AS WELL AS METHOD FOR MANUFACTURING (E, Z)-N-MONOALKYL-3-OXO-3-(2-THIENYL) PROPENAMINE | SUMITOMO SEIKA CHEM CO LTD | 2013-12-26 | — | — | JP | disclosed |
| JP-5361187-B2 | — | — | 2013-12-04 | — | — | JP | disclosed |
| CN-101535260-B | Thiophene compounds | NAT HEALTH RESEARCH INSTITUTES | 2012-07-04 | — | — | CN | disclosed |
| CN-101870700-B | Method for synthesizing Indiplon | UNIV PLA 3RD MILITARY MEDICAL | 2012-05-23 | — | — | CN | disclosed |
| CN-101870700-A | Method for synthesizing Indiplon | UNIV PLA 3RD MILITARY MEDICAL | 2010-10-27 | — | — | CN | disclosed |
| CN-101535260-A | Thiophene compounds | NAT HEALTH RESEARCH INSTITUTES (CN) | 2009-09-16 | — | — | CN | disclosed |
| US-7365085-B2 | Compounds and methods | SMITHKLINE BEECHAM CORPORATION (US) | 2008-04-29 | — | — | US | disclosed |
| EP-1575495-A2 | COMPOUNDS AND METHODS | SmithKline Beecham Corporation (US) | 2005-09-21 | — | — | EP | disclosed |
| US-20050113580-A1 | Amide compounds and methods of using the same | SMITHKLINE BEECHAM CORP | 2005-05-26 | — | — | US | disclosed |
| WO-2003082205-A2 | COMPOUNDS AND METHODS | SMITHKLINE BEECHAM CORPORATION (US) | 2003-10-09 | — | — | WO | disclosed |
| CN-1329648-A | Material consisting of cyanoacrylate and aldehyde-or ketone-condensation products for adhesives, coatings and sealants | HENKEL KGAA (DE) | 2002-01-02 | — | — | CN | disclosed |
| CN-1252070-A | 5,7-disubstituted 4-aminopyrido [2,3,-d] pyrimidine compounds and their use as adenosine kinase inhibitors | ABBOTT LAB (US) | 2000-05-03 | — | — | CN | disclosed |
| EP-0274434-A1 | Dopamine-beta-hydroxylase inhibitors | SMITHKLINE BEECHAM CORPORATION (US) | 1988-07-13 | — | — | EP | disclosed |
| US-4749717-A | 1-(2- OR 3-THIENYLALKYL)IMIDAZOLE-2-THIOLS AND 1-(2- OR 3-THIENYLALKYL)-2-ALKLYTHIOMIDAZOLES; HYPOTENSIVE AGENT, DIURETIC | SMITHKLINE BECKMAN CORPORATION (US) | 1988-06-07 | — | — | US | disclosed |
| EP-0244195-A1 | 2-Vinylpenams and process | THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD (GB) | 1987-11-04 | — | — | EP | disclosed |
| US-4087549-A | Sulphonic acid containing indenyl derivatives | MERCK & CO., INC. (US) | 1978-05-02 | — | — | US | disclosed |