Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 9/20 | 0.35 |
| ▸ | PPARA | Q07869 | 2/20 | 0.35 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | ACACB | O00763 | 1/20 | 0.33 |
| ▸ | RXRA | P19793 | 1/20 | 0.32 |
| ▸ | HNF4A | P41235 | 1/20 | 0.32 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP26B1 | Q9NR63 | 1/20 | 0.32 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4950350 | 0.97 | MAOA (0.35) | MRGPRX4PPARAPTGER1MAOAMAOB | |
| SCHEMBL4948101 | 0.88 | RARB (0.41) | MRGPRX4PPARAPTGER1MAOAMAOB | |
| SCHEMBL4946301 | 0.84 | CYP3A4 (0.39) | MRGPRX4PPARAMAOAMAOBCYP26A1 | |
| SCHEMBL4951005 | 0.80 | NR4A2 (0.49) | MRGPRX4PPARAMAOBRXRAHNF4A | |
| SCHEMBL4947926 | 0.80 | NR4A2 (0.44) | MRGPRX4PTGER1RXRAHNF4ACYP26A1 | |
| SCHEMBL4948642 | 0.79 | RARB (0.41) | MRGPRX4RXRACYP26A1CYP3A4CYP26B1 | |
| SCHEMBL4943814 | 0.78 | NR4A2 (0.44) | MRGPRX4PTGER1RXRAHNF4ACYP26A1 | |
| SCHEMBL4942429 | 0.78 | RARB (0.43) | MRGPRX4MAOBRXRAHNF4ACYP26A1 | |
| SCHEMBL4948843 | 0.77 | RARB (0.44) | MRGPRX4RXRAHNF4ACYP26A1CYP3A4 | |
| SCHEMBL4945312 | 0.77 | MRGPRX4 (0.43) | MRGPRX4MAOAMAOBACACBCYP26A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1513803-B1 | LIGANDS THAT ARE INHIBITORS OF THE RAR RECEPTORS | GALDERMA RES & DEV (FR) | 2008-06-18 | — | — | EP | claimed |