Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHKA | P35790 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | KDM1A | O60341 | 2/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | DDR1 | Q08345 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | DDR2 | Q16832 | 2/20 | 0.42 |
| ▸ | ABL1 | P00519 | 1/20 | 0.42 |
| ▸ | BCR | P11274 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24071005 | 0.89 | CYP2D6 (0.53) | CHKAALDH1A1KDM1ADDR1TSHR | |
| SCHEMBL3934249 | 0.87 | CHKA (0.48) | CHKAALDH1A1MAPTKDM4EKDM1A | |
| SCHEMBL4949624 | 0.85 | ALDH1A1 (0.55) | ALDH1A1MAPTKDM4EHDAC6DDR1 | |
| SCHEMBL16829150 | 0.82 | CHKA (0.55) | CHKAALDH1A1MAPTKDM4EKDM1A | |
| SCHEMBL23013004 | 0.82 | CHKA (0.58) | CHKAALDH1A1MAPTKDM4EKDM1A | |
| SCHEMBL30339886 | 0.79 | NOTUM (0.58) | CHKAALDH1A1KDM1ADDR1TSHR | |
| SCHEMBL16829120 | 0.79 | CHKA (0.52) | CHKAALDH1A1MAPTKDM1AHDAC6 | |
| SCHEMBL10145077 | 0.77 | ALDH1A1 (0.60) | CHKAALDH1A1MAPTHDAC6MEN1 | |
| SCHEMBL31721209 | 0.77 | ALDH1A1 (0.60) | CHKAALDH1A1MAPTHDAC6MEN1 | |
| SCHEMBL14293711 | 0.77 | NOTUM (0.49) | ALDH1A1KDM4ELMNAPOLBGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008089034-A2 | CYTOKINE INHIBITORS | KEMIA, INC. (US) | 2008-07-24 | — | — | WO | disclosed |