Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 19/20 | 0.49 |
| ▸ | CDK8 | P49336 | 7/20 | 0.49 |
| ▸ | MAPK9 | P45984 | 5/20 | 0.49 |
| ▸ | MAPK13 | O15264 | 3/20 | 0.46 |
| ▸ | MAPK12 | P53778 | 3/20 | 0.46 |
| ▸ | MAPK11 | Q15759 | 3/20 | 0.46 |
| ▸ | CSNK1A1 | P48729 | 2/20 | 0.45 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.44 |
| ▸ | DDR2 | Q16832 | 2/20 | 0.44 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1600301 | 0.94 | MAPK14 (0.54) | MAPK14CDK8MAPK9MAPK13MAPK12 | |
| SCHEMBL1598985 | 0.87 | MAPK14 (0.61) | MAPK14CDK8MAPK9MAPK13MAPK12 | |
| SCHEMBL1601140 | 0.86 | MAPK14 (0.51) | MAPK14CDK8MAPK9MAPK13MAPK12 | |
| SCHEMBL1599290 | 0.81 | MAPK14 (0.59) | MAPK14CDK8MAPK9MAPK13MAPK12 | |
| SCHEMBL1599053 | 0.79 | MAPK14 (0.57) | MAPK14CDK8MAPK9MAPK13MAPK12 | |
| SCHEMBL4946702 | 0.77 | MAPK14 (0.60) | MAPK14CDK8MAPK9MAPK13MAPK12 | |
| SCHEMBL1600323 | 0.76 | MAPK14 (0.63) | MAPK14CDK8MAPK9MAPK13MAPK12 | |
| SCHEMBL4944531 | 0.75 | MAPK14 (0.54) | MAPK14 | |
| SCHEMBL1600345 | 0.74 | MAPK14 (0.53) | MAPK14CDK8MAPK9MAPK13MAPK12 | |
| SCHEMBL4944631 | 0.74 | MAPK14 (0.52) | MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008089034-A2 | CYTOKINE INHIBITORS | KEMIA, INC. (US) | 2008-07-24 | — | — | WO | disclosed |