Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MIF | P14174 | 6/20 | 0.32 |
| ▸ | CALML3 | P27482 | 1/20 | 0.32 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.32 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4950987 | 0.81 | POLB (0.46) | HDAC6POLBMIFITGB3ITGA2B | |
| SCHEMBL3984480 | 0.79 | HDAC6 (0.39) | HDAC6POLBMIFITGB3ITGA2B | |
| SCHEMBL2673670 | 0.71 | MIF (0.44) | HDAC6MIF | |
| SCHEMBL3986285 | 0.69 | HDAC6 (0.41) | HDAC6MAPT | |
| SCHEMBL3986321 | 0.69 | MIF (0.46) | HDAC6MIF | |
| SCHEMBL7508023 | 0.69 | MIF (0.46) | HDAC6MIF | |
| SCHEMBL3985978 | 0.67 | HDAC6 (0.50) | HDAC6MIFCALML3 | |
| SCHEMBL29644199 | 0.66 | MIF (0.44) | MIF | |
| SCHEMBL3984080 | 0.66 | F2 (0.40) | — | |
| SCHEMBL6853296 | 0.64 | POLB (0.53) | POLBMIF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1893572-A2 | FACTOR XA INHIBITORS | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2008-03-05 | — | — | EP | disclosed |
| WO-2006002099-A2 | FACTOR XA INHIBITORS | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2006-01-05 | — | — | WO | disclosed |