Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 20/20 | 0.57 |
| ▸ | PPARA | Q07869 | 5/20 | 0.54 |
| ▸ | PPARG | P37231 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14188775 | 0.95 | PPARD (0.55) | PPARDPPARAPPARG | |
| Mbx-8025 SCHEMBL4950228 | 0.91 | PPARD (0.61) | PPARDPPARAPPARG | |
| SCHEMBL14188773 | 0.90 | PPARD (0.46) | PPARDPPARAPPARG | |
| SCHEMBL4956335 | 0.87 | PPARD (0.58) | PPARDPPARAPPARG | |
| SCHEMBL4953848 | 0.86 | PPARD (0.60) | PPARDPPARAPPARG | |
| SCHEMBL14188770 | 0.85 | PPARD (0.44) | PPARDPPARAPPARG | |
| SCHEMBL4954172 | 0.85 | PPARD (0.58) | PPARDPPARAPPARG | |
| SCHEMBL4953173 | 0.84 | PPARD (0.60) | PPARDPPARAPPARG | |
| SCHEMBL4954329 | 0.84 | PPARD (0.59) | PPARDPPARAPPARG | |
| SCHEMBL4950397 | 0.83 | PPARD (0.56) | PPARDPPARAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080108630-A1 | SUBSTITUTED TRIAZOLES AS MODULATORS OF PPAR AND METHODS OF THEIR PREPARATION | METABOLEX INC. (US) | 2008-05-08 | — | — | US | claimed |
| EP-1751120-A2 | SUBSTITUTED TRIAZOLES AS MODULATORS OF PPAR AND METHODS OF THEIR PREPARATION | METABOLEX, INC. (US) | 2007-02-14 | — | — | EP | claimed |
| US-20060014809-A1 | Substituted triazoles as modulators of PPAR and methods of their preparation | METABOLEX, INC. (US) | 2006-01-19 | — | — | US | claimed |
| WO-2005115383-A2 | SUBSTITUTED TRIAZOLES AS MODULATORS OF PPAR AND METHODS OF THEIR PREPARATION | METABOLEX, INC. (US) | 2005-12-08 | — | — | WO | claimed |
| US-20080108630-A1 | SUBSTITUTED TRIAZOLES AS MODULATORS OF PPAR AND METHODS OF THEIR PREPARATION | METABOLEX INC. (US) | 2008-05-08 | — | — | US | disclosed |
| US-20080108630-A1 | SUBSTITUTED TRIAZOLES AS MODULATORS OF PPAR AND METHODS OF THEIR PREPARATION | METABOLEX INC. (US) | 2008-05-08 | — | — | US | disclosed |
| US-20080108630-A1 | SUBSTITUTED TRIAZOLES AS MODULATORS OF PPAR AND METHODS OF THEIR PREPARATION | METABOLEX INC. (US) | 2008-05-08 | — | — | US | disclosed |
| US-7323480-B2 | Substituted triazoles as modulators of PPAR and methods of their preparation | METABOLEX, INC. (US) | 2008-01-29 | — | — | US | disclosed |
| US-7323480-B2 | Substituted triazoles as modulators of PPAR and methods of their preparation | METABOLEX, INC. (US) | 2008-01-29 | — | — | US | disclosed |
| US-7323480-B2 | Substituted triazoles as modulators of PPAR and methods of their preparation | METABOLEX, INC. (US) | 2008-01-29 | — | — | US | disclosed |
| EP-1751120-A2 | SUBSTITUTED TRIAZOLES AS MODULATORS OF PPAR AND METHODS OF THEIR PREPARATION | METABOLEX, INC. (US) | 2007-02-14 | — | — | EP | disclosed |
| US-20060014809-A1 | Substituted triazoles as modulators of PPAR and methods of their preparation | METABOLEX, INC. (US) | 2006-01-19 | — | — | US | disclosed |
| WO-2005115383-A2 | SUBSTITUTED TRIAZOLES AS MODULATORS OF PPAR AND METHODS OF THEIR PREPARATION | METABOLEX, INC. (US) | 2005-12-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060014809-A1 | Substituted triazoles as modulators of PPAR and methods of their preparation | PPARG, PPARD, GPR119 | PPARD 2/4885PPARA 4/4885PPARG 1/4885 |
| US-20080108630-A1 | SUBSTITUTED TRIAZOLES AS MODULATORS OF PPAR AND METHODS OF THEIR PREPARATION | PPARG, PPARD, GPR119 | PPARD 2/4885PPARA 4/4885PPARG 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.