Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1318740 | 0.87 | SPHK1 (0.34) | — | |
| SCHEMBL112607 | 0.85 | — | — | |
| SCHEMBL73235 | 0.83 | NPC1 (0.45) | NPC1HPGD | |
| SCHEMBL8802672 | 0.83 | NPC1 (0.45) | NPC1HPGD | |
| SCHEMBL72977 | 0.82 | NPC1 (0.38) | NPC1HPGD | |
| SCHEMBL9035182 | 0.82 | NPC1 (0.38) | NPC1HPGD | |
| SCHEMBL11909720 | 0.82 | NPC1 (0.38) | NPC1HPGD | |
| SCHEMBL6987461 | 0.80 | NPC1 (0.34) | NPC1 | |
| SCHEMBL9566739 | 0.73 | NPC1 (0.42) | NPC1HPGD | |
| SCHEMBL9036075 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008026075-A2 | TREATMENT OF INTRACELLULAR BACTERIAL INFECTIONS WITH A PROTEIN KINASE INHIBITOR OR AN AS160 POLYPEPTIDE ACTIVATOR | VERENIGING HET NEDERLANDS KANKER INSTITUUT (NL) | 2008-03-06 | — | — | WO | disclosed |
| EP-1501822-A1 | PHTHALAZINONE DERIVATIVES | Kudos Pharmaceuticals Limited (GB) | 2005-02-02 | — | — | EP | disclosed |
| WO-2003093261-A1 | PHTHALAZINONE DERIVATIVES | KUDOS PHARMACEUTICALS LIMITED (GB) | 2003-11-13 | — | — | WO | disclosed |