Styrene

Styrene

SCHEMBL4952811

C=Cc1ccccc1.NC(=O)C1=CC(=O)OC1=O

nearest known ligand 0.44

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.44
TSHR P16473 2/20 0.44
MAPT P10636 4/20 0.36
LMNA P02545 2/20 0.36
KDM4E B2RXH2 1/20 0.36
HPGD P15428 1/20 0.36
PARP1 P09874 4/20 0.36
HTT P42858 2/20 0.34
CYP2C19 P33261 2/20 0.33
RECQL P46063 2/20 0.33
POLB P06746 1/20 0.33
CYP3A4 P08684 1/20 0.33
BLM P54132 1/20 0.33
PMP22 Q01453 1/20 0.33
HSD17B10 Q99714 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
HDAC2 Q92769 2/20 0.32
MCL1 Q07820 1/20 0.32
NPC1 O15118 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2382929 0.81 POLB (0.32) TSHRMAPTPARP1CYP2C19RECQL
Styrene SCHEMBL28985366 0.79 TSHR (0.41) ALDH1A1TSHRMAPTHTTRECQL
Styrene SCHEMBL5164588 0.75 ALDH1A1 (0.70) ALDH1A1TSHRMAPTLMNAKDM4E
Styrene SCHEMBL2033347 0.75 ALDH1A1 (0.70) ALDH1A1TSHRMAPTLMNAKDM4E
Styrene SCHEMBL28015835 0.75 ALDH1A1 (0.52) ALDH1A1TSHRMAPTKDM4EHPGD
Styrene SCHEMBL8864895 0.74 ALDH1A1 (0.47) ALDH1A1TSHRMAPTLMNAKDM4E
Styrene SCHEMBL27496207 0.73 ALDH1A1 (0.67) ALDH1A1TSHRMAPTLMNAKDM4E
Styrene SCHEMBL27925811 0.73 ALDH1A1 (0.67) ALDH1A1TSHRMAPTLMNAKDM4E
SCHEMBL28029889 0.73 ALDH1A1 (0.33) ALDH1A1TSHRMAPTKDM4EHPGD
Styrene SCHEMBL3361846 0.73 ALDH1A1 (0.54) ALDH1A1TSHRMAPTLMNAKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1809709-B1 INKJET INKS PROVIDING IMPROVED WET SMUDGE ON POROUS PRINT MEDIA HEWLETT PACKARD DEVELOPMENT CO (US) 2008-10-08 EP disclosed