Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 6/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.33 |
| ▸ | SRC | P12931 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | GFER | P55789 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4949273 | 0.94 | FGFR1 (0.34) | FGFR1ALDH1A1MAPTSMN1; SMN2HCAR3 | |
| SCHEMBL4951893 | 0.87 | FGFR1 (0.37) | FGFR1ALDH1A1MAPTSMN1; SMN2HCAR3 | |
| SCHEMBL4955288 | 0.87 | FGFR1 (0.42) | FGFR1ALDH1A1MAPTSMN1; SMN2HCAR3 | |
| SCHEMBL4953306 | 0.83 | FGFR1 (0.35) | FGFR1ALDH1A1MAPTSMN1; SMN2SRC | |
| SCHEMBL4951849 | 0.79 | FGFR1 (0.33) | FGFR1SRCRAB9A | |
| SCHEMBL4951408 | 0.76 | FGFR1 (0.35) | FGFR1ALDH1A1MAPTSMN1; SMN2SRC | |
| SCHEMBL4952582 | 0.75 | FGFR1 (0.32) | FGFR1SRC | |
| SCHEMBL4953183 | 0.73 | FGFR1 (0.33) | FGFR1ALDH1A1MAPTHCAR3SRC | |
| SCHEMBL4955626 | 0.73 | FGFR1 (0.33) | FGFR1SRC | |
| SCHEMBL4952825 | 0.71 | ALDH1A1 (0.35) | ALDH1A1MAPTSMN1; SMN2KDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7371264-B2 | Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof | THE PROCTER & GAMBLE COMPANY (US) | 2008-05-13 | — | — | US | claimed |
| US-20060042026-A1 | Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof | THE PROCTER & GAMBLE COMPANY (US) | 2006-03-02 | — | — | US | claimed |
| US-7371264-B2 | Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof | THE PROCTER & GAMBLE COMPANY (US) | 2008-05-13 | — | — | US | disclosed |
| CN-101010118-A | Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof | PROCTER & GAMBLE (US) | 2007-08-01 | — | — | CN | disclosed |
| EP-1781379-A1 | KERATIN DYEING COMPOUNDS, KERATIN DYEING COMPOSITIONS CONTAINING THEM, AND USE THEREOF | The Procter and Gamble Company (US) | 2007-05-09 | — | — | EP | disclosed |
| WO-2006026495-A1 | KERATIN DYEING COMPOUNDS, KERATIN DYEING COMPOSITIONS CONTAINING THEM, AND USE THEREOF | THE PROCTER & GAMBLE COMPANY (US) | 2006-03-09 | — | — | WO | disclosed |
| US-20060042026-A1 | Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof | THE PROCTER & GAMBLE COMPANY (US) | 2006-03-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060042026-A1 | Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof | KRT18, KDM5A, KDM5C | FGFR1 3538/4885ALDH1A1 510/4885MAPT 1139/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.