Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 4/20 | 0.56 |
| ▸ | SLC22A1 | O15245 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL16395834 | 0.98 | DNM1 (0.54) | DNM1SLC22A1ALDH1A1TP53CYP3A4 | |
| SCHEMBL11880850 | 0.96 | DNM1 (0.56) | DNM1SLC22A1ALDH1A1TP53CYP3A4 | |
| Water SCHEMBL9000170 | 0.94 | DNM1 (0.54) | DNM1SLC22A1ALDH1A1TP53CYP3A4 | |
| SCHEMBL28558958 | 0.94 | SLC22A1 (0.56) | DNM1SLC22A1ALDH1A1TP53CYP3A4 | |
| SCHEMBL12109955 | 0.94 | SLC22A1 (0.56) | DNM1SLC22A1ALDH1A1TP53CYP3A4 | |
| SCHEMBL17991832 | 0.92 | SLC22A1 (0.44) | DNM1SLC22A1ALDH1A1TP53CYP3A4 | |
| SCHEMBL6236411 | 0.90 | SLC22A1 (0.52) | DNM1SLC22A1ALDH1A1TP53CYP3A4 | |
| SCHEMBL29506651 | 0.90 | SLC22A1 (0.56) | DNM1SLC22A1ALDH1A1TP53CYP3A4 | |
| SCHEMBL10138705 | 0.90 | SLC22A1 (0.56) | DNM1SLC22A1ALDH1A1TP53CYP3A4 | |
| Tetrahexylammonium SCHEMBL27604612 | 0.90 | SLC22A1 (0.56) | DNM1SLC22A1ALDH1A1TP53CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080025993-A1 | Method for Refolding Neisserial Nspa Protein | GLAXOSMITHKLINE BIOLOGICALS SA (BE) | 2008-01-31 | — | — | US | disclosed |