Hematoxylin

Hematoxylin

SCHEMBL4954328

Oc1cc2c(cc1O)[C@H]1c3ccc(O)c(O)c3OC[C@@]1(O)C2.[BiH3]

nearest known ligand 0.97

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.97
KDM4E B2RXH2 4/20 0.97
HPGD P15428 4/20 0.97
MAPK1 P28482 4/20 0.97
RECQL P46063 3/20 0.97
TDP1 Q9NUW8 3/20 0.97
ALDH1A1 P00352 3/20 0.97
CYP3A4 P08684 3/20 0.97
HSD17B10 Q99714 3/20 0.97
MET P08581 3/20 0.97
KIT P10721 3/20 0.97
FGFR1 P11362 3/20 0.97
SRC P12931 3/20 0.97
KDR P35968 3/20 0.97
G6PD P11413 2/20 0.97
L3MBTL1 Q9Y468 2/20 0.97
MEN1 O00255 2/20 0.97
ALOX15 P16050 2/20 0.97
KMT2A Q03164 2/20 0.97
NSD2 O96028 1/20 0.97

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Haematoxylin SCHEMBL29366910 0.99 MAPT (1.00) MAPTKDM4EHPGDMAPK1RECQL
Hematoxylin SCHEMBL29357236 0.99 MAPT (1.00) MAPTKDM4EHPGDMAPK1RECQL
Haematoxylin SCHEMBL1784957 0.99 MAPT (1.00) MAPTKDM4EHPGDMAPK1RECQL
Haematoxylin SCHEMBL29360033 0.99 MAPT (1.00) MAPTKDM4EHPGDMAPK1RECQL
Haematoxylin SCHEMBL30101752 0.99 MAPT (1.00) MAPTKDM4EHPGDMAPK1RECQL
Hematoxylin SCHEMBL30089789 0.99 MAPT (1.00) MAPTKDM4EHPGDMAPK1RECQL
Hematoxylin SCHEMBL7026124 0.99 MAPT (1.00) MAPTKDM4EHPGDMAPK1RECQL
Hematoxylin SCHEMBL19654 0.99 MAPT (1.00) MAPTKDM4EHPGDMAPK1RECQL
Hematoxylin SCHEMBL1747 0.99 MAPT (1.00) MAPTKDM4EHPGDMAPK1RECQL
Hematoxylin SCHEMBL29363003 0.99 MAPT (1.00) MAPTKDM4EHPGDMAPK1RECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2469263-A1 Biological sample processing composition and method Ventana Medical Systems, Inc. (US) 2012-06-27 EP disclosed
EP-1977214-A2 BIOLOGICAL SAMPLE PROCESSING COMPOSITION AND METHOD Ventana Medical Systems, Inc. (US) 2008-10-08 EP disclosed
WO-2007084429-A2 BIOLOGICAL SAMPLE PROCESSING COMPOSITION AND METHOD VENTANA MEDICAL SYSTEMS, INC. (US) 2007-07-26 WO disclosed
US-20070172911-A1 Biological sample processing composition and method VENTANA MEDICAL SYSTEMS, INC. 2007-07-26 US disclosed