Haematoxylin

Haematoxylin

SCHEMBL1784957

Oc1cc2c(cc1O)C1c3ccc(O)c(O)c3OCC1(O)C2

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 1.00
KDM4E B2RXH2 4/20 1.00
HPGD P15428 4/20 1.00
MAPK1 P28482 4/20 1.00
RECQL P46063 3/20 1.00
TDP1 Q9NUW8 3/20 1.00
ALDH1A1 P00352 3/20 1.00
CYP3A4 P08684 3/20 1.00
HSD17B10 Q99714 3/20 1.00
MET P08581 3/20 1.00
KIT P10721 3/20 1.00
FGFR1 P11362 3/20 1.00
SRC P12931 3/20 1.00
KDR P35968 3/20 1.00
G6PD P11413 2/20 1.00
L3MBTL1 Q9Y468 2/20 1.00
MEN1 O00255 2/20 1.00
ALOX15 P16050 2/20 1.00
KMT2A Q03164 2/20 1.00
NSD2 O96028 1/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hematoxylin SCHEMBL29363003 1.00 MAPT (1.00) MAPTKDM4EHPGDMAPK1RECQL
Hematoxylin SCHEMBL30089789 1.00 MAPT (1.00) MAPTKDM4EHPGDMAPK1RECQL
Haematoxylin SCHEMBL29366910 1.00 MAPT (1.00) MAPTKDM4EHPGDMAPK1RECQL
Haematoxylin SCHEMBL29360033 1.00 MAPT (1.00) MAPTKDM4EHPGDMAPK1RECQL
Haematoxylin SCHEMBL30101752 1.00 MAPT (1.00) MAPTKDM4EHPGDMAPK1RECQL
Hematoxylin SCHEMBL7026124 1.00 MAPT (1.00) MAPTKDM4EHPGDMAPK1RECQL
Hematoxylin SCHEMBL29357236 1.00 MAPT (1.00) MAPTKDM4EHPGDMAPK1RECQL
Hematoxylin SCHEMBL19654 1.00 MAPT (1.00) MAPTKDM4EHPGDMAPK1RECQL
Hematoxylin SCHEMBL1747 1.00 MAPT (1.00) MAPTKDM4EHPGDMAPK1RECQL
Hematoxylin SCHEMBL19816198 0.99 MAPT (0.97) MAPTKDM4EHPGDMAPK1RECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 180 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3636600-B1 A SORPTION COMPOSITION FOR COMPLEX WATER PURIFICATION EWI BVBA (BE) 2022-11-30 EP claimed
EP-3636600-A1 A SORPTION COMPOSITION FOR COMPLEX WATER PURIFICATION EWI bvba (BE) 2020-04-15 EP claimed
JP-60222130-A None JP disclosed
US-20230280578-A1 PARAFFIN SHIELD COATING FOR MICROSCOPE SLIDE SHENZHEN PRS LIMITED (CN) 2023-09-07 US disclosed
US-20230280578-A1 PARAFFIN SHIELD COATING FOR MICROSCOPE SLIDE SHENZHEN PRS LIMITED (CN) 2023-09-07 US disclosed
US-20230190761-A1 METHYLENE BLUE STABILIZED MRNA COMPOSITIONS MODERNATX, INC. (US) 2023-06-22 US disclosed
US-11662564-B2 Paraffin shield coating for microscope slide SHENZHEN PRS LIMITED (CN) 2023-05-30 US disclosed
US-11662564-B2 Paraffin shield coating for microscope slide SHENZHEN PRS LIMITED (CN) 2023-05-30 US disclosed
US-11561155-B2 Heavy metal ion-hematein-complexes useful as ex vivo contrast agent for a computed tomography scanning of a biological sample, ex vivo method for investigating a biological sample, and use of the complexes Technische Universität München (DE) 2023-01-24 US disclosed
EP-3636600-B1 A SORPTION COMPOSITION FOR COMPLEX WATER PURIFICATION EWI BVBA (BE) 2022-11-30 EP disclosed
US-20220098549-A1 METHOD FOR CHARACTERISING A TISSUE-ENGINEERED CONSTRUCT 1LAB SA (CH) 2022-03-31 US disclosed
US-6054256-A COLORIMETRIC ANALYSIS; DETECTING DOSAGE RADIATION KIMBERLY-CLARK WORLDWIDE, INC. (US) 2000-04-25 US disclosed
US-6033465-A Colorants and colorant modifiers KIMBERLY-CLARK WORLDWIDE, INC. (US) 2000-03-07 US disclosed
US-6017471-A A RADIATION TRANSORBER CAPABLE OF MUTATING A COLORANT; LIGHT-STABLE COLORANT SYSTEM THAT IS MUTABLE BY EXPOSURE TO NARROW BAND-WIDTH RADIATION; COLORFASTNESS; DRY IMAGING; ?ERASING? COLORANTS; DATA STORAGE DISKS KIMBERLY-CLARK WORLDWIDE, INC. (US) 2000-01-25 US disclosed
US-6017661-A SUBSTRATE SURFACE ATTACHED TO MERCHANDISE AND LABELED WITH INDICIA COMPRISING A MUTABLE COLORANT, MOLECULAR INCLUDANT AND A TRANSORBER WHICH IRREVERSIBLY DECOLORS COLORANT UPON EXPOSURE TO ULTRAVIOLET RADIATION KIMBERLY-CLARK CORPORATION (US) 2000-01-25 US disclosed
US-5645964-A STABILIZERS KIMBERLY-CLARK CORPORATION (US) 1997-07-08 US disclosed
US-5643701-A Electrophotgraphic process utilizing mutable colored composition KIMBERLY-CLARK CORPORATION (US) 1997-07-01 US disclosed
US-5616443-A TONER FOR ELECTROGRAPHY KIMBERLY-CLARK CORPORATION (US) 1997-04-01 US disclosed
JP-S60222130-A DEODORANT LION CORP 1985-11-06 JP disclosed
US-3997656-A TRICHLOROACETIC ACID, ZINC CHLORIDE, FORMALDEHYDE APPLIED BIOSCIENCE (US) 1976-12-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11561155-B2 Heavy metal ion-hematein-complexes useful as ex vivo contrast agent for a computed tomography scanning of a biological sample, ex vivo method for investigating a biological sample, and use of the complexes SERPINC1, CD63, CD68 MAPT 3682/4885KDM4E 4785/4885HPGD 3139/4885
US-20230190761-A1 METHYLENE BLUE STABILIZED MRNA COMPOSITIONS LMNB2, NSUN2, RNMT MAPT 470/4885KDM4E 333/4885HPGD 3443/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.