Benzylsulfamide

Benzylsulfamide

SCHEMBL49548

NS(=O)(=O)c1ccc(NCc2ccccc2)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CA2 P00918 15/20 1.00
CA1 P00915 14/20 1.00
CA9 Q16790 10/20 1.00
CA12 O43570 10/20 1.00
ALDH1A1 P00352 1/20 0.61
HPGD P15428 1/20 0.61
CA7 P43166 2/20 0.60
CYP1A2 P05177 1/20 0.59
CA4 P22748 1/20 0.59
CA5A P35218 1/20 0.58
CA14 Q9ULX7 1/20 0.58
CA5B Q9Y2D0 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzylsulfamide SCHEMBL3648127 0.98 CA1 (0.97) CA2CA1CA9CA12ALDH1A1
Benzylsulfamide SCHEMBL28249531 0.91 CA1 (0.82) CA2CA1CA9CA12ALDH1A1
SCHEMBL28936690 0.83 CA2 (0.71) CA2CA1CA9CA12ALDH1A1
SCHEMBL11214389 0.82 CA2 (0.70) CA2CA1CA9CA12ALDH1A1
SCHEMBL9189617 0.82 CA1 (0.70) CA2CA1CA9CA12ALDH1A1
SCHEMBL7265159 0.81 CA1 (0.69) CA2CA1CA9CA12ALDH1A1
SCHEMBL17813135 0.81 CA2 (0.68) CA2CA1CA9CA12CA7
SCHEMBL20899654 0.81 CA2 (0.68) CA2CA1CA9CA12ALDH1A1
SCHEMBL11214392 0.81 CA1 (0.68) CA2CA1CA9CA12ALDH1A1
SCHEMBL28535501 0.81 CA1 (0.68) CA2CA1CA9CA12ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1695 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250099557-A1 ANTIBIOTIC PHARMACEUTICAL COMPOSITION CAPABLE OF SUBCUTANEOUS ADMINISTRATION SHANGHAI BAO PHARMACEUTICALS CO., LTD. (CN) 2025-03-27 US claimed
EP-4374848-A1 ANTIBIOTIC PHARMACEUTICAL COMPOSITION CAPABLE OF SUBCUTANEOUS ADMINISTRATION Shanghai Bao Pharmaceuticals Co., Ltd. (CN) 2024-05-29 EP claimed
CN-111518053-B 4-benzyl amino benzene sulfonamide derivative, preparation and application thereof 武汉赛莱亚生物科技有限公司 2023-03-14 CN claimed
CN-111518053-A 4-benzyl amino benzene sulfonamide derivative, preparation and application thereof 武汉大学 2020-08-11 CN claimed
US-10449247-B2 Compositions and methods for enhancing immune response AVIVAGEN INC. (CA) 2019-10-22 US claimed
US-9016221-B2 Surface topographies for non-toxic bioadhesion control UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2015-04-28 US claimed
US-8993117-B2 Devices with multiple surface functionality THE TRUSTEES OF PRINCETON UNIVERSITY (US) 2015-03-31 US claimed
CN-103483274-A Method for preparing bensulfuron methyl JIANGSU KUAIDA AGROCHEMICAL CO LTD 2014-01-01 CN claimed
EP-2560634-A1 NITRIC OXIDE RELEASING PRODRUGS OF THERAPEUTIC AGENTS Piramal Enterprises Limited (IN) 2013-02-27 EP claimed
US-8361492-B2 Drug delivery system and methods of use Ocugenics, LLC (US) 2013-01-29 US claimed
EP-0786999-A4 COMBINATION METHOD FOR ACNE TREATMENT MERCK & CO INC (US) 1999-01-20 EP claimed
EP-0792371-A4 COMBINATION METHOD FOR ACNE TREATMENT MERCK & CO INC (US) 1998-12-30 EP claimed
EP-0792371-A1 COMBINATION METHOD FOR ACNE TREATMENT Merck & Co., Inc. (US) 1997-09-03 EP claimed
EP-0786999-A1 COMBINATION METHOD FOR ACNE TREATMENT Merck & Co., Inc. (US) 1997-08-06 EP claimed
EP-0741570-A1 METHOD FOR PREVENTING OR REDUCING PHOTOSENSITIVITY AND/OR PHOTOTOXICITY REACTIONS TO MEDICATIONS G.D. SEARLE & CO. (US) 1996-11-13 EP claimed
US-5543417-A 5 Alpha-reductase inhibitor and at least one of an antibacterial agent, a keratolytic agent or an anti-inflammatory agent MERCK & CO., INC. (US) 1996-08-06 US claimed
WO-1996012487-A1 COMBINATION METHOD FOR ACNE TREATMENT MERCK & CO., INC. (US) 1996-05-02 WO claimed
WO-1996012817-A1 COMBINATION METHOD FOR ACNE TREATMENT MERCK & CO., INC. (US) 1996-05-02 WO claimed
WO-1995020387-A1 METHOD FOR PREVENTING OR REDUCING PHOTOSENSITIVITY AND/OR PHOTOTOXICITY REACTIONS TO MEDICATIONS G.D. SEARLE & CO. (US) 1995-08-03 WO claimed
EP-0075172-B1 N-SULFENYL BENZYLSULFONE AMIDES, PREPARATION AND THEIR USE AS MICROBICIDES BAYER AG (DE) 1985-05-29 EP claimed