Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 7/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 4/20 | 0.33 |
| ▸ | CA2 | P00918 | 4/20 | 0.33 |
| ▸ | CA12 | O43570 | 3/20 | 0.33 |
| ▸ | CA9 | Q16790 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18413700 | 0.83 | APP (0.42) | APPMAPTGAAMAOAMAOB | |
| SCHEMBL19958976 | 0.81 | HRH3 (0.45) | MAPTGAACA1CA2MEN1 | |
| SCHEMBL128126 | 0.79 | MAPT (0.47) | APPMAPTGAAMAOAMAOB | |
| SCHEMBL14028540 | 0.78 | CYP3A4 (0.41) | MAPTALDH1A1CYP1A2CYP3A4CYP2C19 | |
| Hydrochloric Acid SCHEMBL9680720 | 0.77 | KCNH3 (0.49) | APPMAPTGAANR4A1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL3337783 | 0.77 | KCNH3 (0.49) | APPMAPTGAANR4A1ALDH1A1 | |
| SCHEMBL6654257 | 0.76 | APP (0.46) | APPMAPTGAAMAOAMAOB | |
| SCHEMBL1023793 | 0.76 | APP (0.37) | APPMAPTGAAMAOAMAOB | |
| SCHEMBL3990484 | 0.76 | APP (0.38) | APPMAPTGAAMAOAMAOB | |
| SCHEMBL147856 | 0.76 | APP (0.42) | APPMAPTGAAMAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1568684-A1 | para-phenylenediamines carrying an alkoxy group, dye composition, preparation methods and their use | L'OREAL (FR) | 2005-08-31 | — | — | EP | claimed |
| US-7435267-B2 | Secondary para-phenylenediamines bearing an alkoxy group, dye composition comprising them, processes therefor and uses thereof | L'OREAL S.A. (FR) | 2008-10-14 | — | — | US | disclosed |
| US-7435267-B2 | Secondary para-phenylenediamines bearing an alkoxy group, dye composition comprising them, processes therefor and uses thereof | L'OREAL S.A. (FR) | 2008-10-14 | — | — | US | disclosed |
| US-7435267-B2 | Secondary para-phenylenediamines bearing an alkoxy group, dye composition comprising them, processes therefor and uses thereof | L'OREAL S.A. (FR) | 2008-10-14 | — | — | US | disclosed |
| US-20060021158-A1 | Secondary para-phenylenediamines bearing an alkoxy group, dye composition comprising them, processes therefor and uses thereof | L'OREAL S.A. (FR) | 2006-02-02 | — | — | US | disclosed |
| EP-1568684-A1 | para-phenylenediamines carrying an alkoxy group, dye composition, preparation methods and their use | L'OREAL (FR) | 2005-08-31 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060021158-A1 | Secondary para-phenylenediamines bearing an alkoxy group, dye composition comprising them, processes therefor and uses thereof | KRT18, NOTUM, ALDH7A1 | APP 446/4885MAPT 2001/4885GAA 4529/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.