Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.37 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.37 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | PLK1 | P53350 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4953919 | 0.93 | ALDH1A1 (0.43) | ALDH1A1ALOX15HTTSMN1; SMN2LMNA | |
| SCHEMBL4951768 | 0.90 | ALDH1A1 (0.44) | ALDH1A1ALOX15HTTSMN1; SMN2LMNA | |
| SCHEMBL4951418 | 0.89 | ALDH1A1 (0.46) | ALDH1A1ALOX15HTTSMN1; SMN2LMNA | |
| SCHEMBL4948995 | 0.89 | ALDH1A1 (0.40) | ALDH1A1ALOX15HTTSMN1; SMN2LMNA | |
| SCHEMBL14859509 | 0.85 | PDE10A (0.35) | ALDH1A1SMN1; SMN2LMNAKDM4EADORA3 | |
| SCHEMBL4951376 | 0.83 | ALDH1A1 (0.45) | ALDH1A1ALOX15HTTSMN1; SMN2RAB9A | |
| SCHEMBL4954177 | 0.81 | ALDH1A1 (0.39) | ALDH1A1ALOX15HTTSMN1; SMN2LMNA | |
| SCHEMBL6175940 | 0.81 | ALDH1A1 (0.44) | ALDH1A1ALOX15HTTSMN1; SMN2LMNA | |
| SCHEMBL4953065 | 0.78 | ALDH1A1 (0.34) | ALDH1A1 | |
| SCHEMBL4954671 | 0.77 | ALDH1A1 (0.55) | ALDH1A1ALOX15HTTSMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7371764-B2 | Quinolin-isoquinolin-and quinazolin-oxyalkylamides and their use as fungicides | SYNGENTA LIMITED (GB) | 2008-05-13 | — | — | US | disclosed |
| EP-1567010-B1 | QUINOLIN-, ISOQUINOLIN-, AND QUINAZOLIN-OXYALKYLAMIDES AND THEIR USE AS FUNGICIDES | SYNGENTA LTD (GB) | 2007-10-24 | — | — | EP | disclosed |
| US-20070072884-A1 | QUINOLIN-ISOQUINOLIN-AND QUINAZOLIN-OXYALKYLAMIDES AND THEIR USE AS FUNGICIDES | SYNGENTA LIMITED (GB) | 2007-03-29 | — | — | US | disclosed |
| US-7122672-B2 | Quinolin-, isoquinolin-, and quinazolin-oxyalkylamides and their use as fungicides | SYNGENTA LIMITED (GB) | 2006-10-17 | — | — | US | disclosed |
| US-20060019973-A1 | Quinolin-,isoquinolin-,and quinazolin-oxyalkylamides and their use as fungicides | SYNGENTA LIMITED (GB) | 2006-01-26 | — | — | US | disclosed |
| EP-1567010-A1 | QUINOLIN-, ISOQUINOLIN-, AND QUINAZOLIN-OXYALKYLAMIDES AND THEIR USE AS FUNGICIDES | Syngenta Limited (GB) | 2005-08-31 | — | — | EP | disclosed |
| WO-2004047538-A1 | QUINOLIN-, ISOQUINOLIN-, AND QUINAZOLIN-OXYALKYLAMIDES AND THEIR USE AS FUNGICIDES | SYNGENTA LIMITED (GB) | 2004-06-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070072884-A1 | QUINOLIN-ISOQUINOLIN-AND QUINAZOLIN-OXYALKYLAMIDES AND THEIR USE AS FUNGICIDES | CBR3, CBR1, POR | ALDH1A1 2830/4885ALOX15 2951/4885HTT 3157/4885 |
| US-20060019973-A1 | Quinolin-,isoquinolin-,and quinazolin-oxyalkylamides and their use as fungicides | CYP4X1, CYP51A1, CYP1A2 | ALDH1A1 896/4885ALOX15 2660/4885HTT 2657/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.