Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 12/20 | 0.84 |
| ▸ | GRIN2B | Q13224 | 12/20 | 0.84 |
| ▸ | GRIN2D | O15399 | 10/20 | 0.84 |
| ▸ | GRIN3B | O60391 | 10/20 | 0.84 |
| ▸ | GRIN2A | Q12879 | 10/20 | 0.84 |
| ▸ | GRIN2C | Q14957 | 10/20 | 0.84 |
| ▸ | GRIN3A | Q8TCU5 | 10/20 | 0.84 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.61 |
| ▸ | OGT | O15294 | 1/20 | 0.49 |
| ▸ | FAAH | O00519 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4578168 | 0.92 | GRIN1 (1.00) | GRIN1GRIN2BGRIN2DGRIN3BGRIN2A | |
| SCHEMBL4551727 | 0.84 | GRIN1 (1.00) | GRIN1GRIN2BGRIN2DGRIN3BGRIN2A | |
| SCHEMBL28766004 | 0.83 | GRIN1 (0.83) | GRIN1GRIN2BGRIN2DGRIN3BGRIN2A | |
| SCHEMBL4551857 | 0.82 | GRIN1 (1.00) | GRIN1GRIN2BGRIN2DGRIN3BGRIN2A | |
| SCHEMBL4577730 | 0.82 | GRIN1 (0.83) | GRIN1GRIN2BGRIN2DGRIN3BGRIN2A | |
| SCHEMBL4552255 | 0.82 | GRIN1 (0.82) | GRIN1GRIN2BGRIN2DGRIN3BGRIN2A | |
| SCHEMBL4577945 | 0.82 | GRIN1 (0.82) | GRIN1GRIN2BGRIN2DGRIN3BGRIN2A | |
| SCHEMBL4577642 | 0.81 | GRIN1 (0.70) | GRIN1GRIN2BGRIN2DGRIN3BGRIN2A | |
| SCHEMBL4955449 | 0.80 | GRIN1 (0.57) | GRIN1GRIN2BGRIN2DGRIN3BGRIN2A | |
| SCHEMBL4577421 | 0.79 | GRIN1 (0.82) | GRIN1GRIN2BGRIN2DGRIN3BGRIN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1409477-B1 | PIPERIDINE DERIVATIVES AS NMDA RECEPTOR ANTAGONISTS | RICHTER GEDEON NYRT (HU) | 2008-09-17 | — | — | EP | claimed |