Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 11/20 | 0.57 |
| ▸ | GRIN2B | Q13224 | 11/20 | 0.57 |
| ▸ | GRIN2D | O15399 | 9/20 | 0.57 |
| ▸ | GRIN3B | O60391 | 9/20 | 0.57 |
| ▸ | GRIN2A | Q12879 | 9/20 | 0.57 |
| ▸ | GRIN2C | Q14957 | 9/20 | 0.57 |
| ▸ | GRIN3A | Q8TCU5 | 9/20 | 0.57 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.50 |
| ▸ | FAAH | O00519 | 2/20 | 0.45 |
| ▸ | CCR5 | P51681 | 1/20 | 0.41 |
| ▸ | OGT | O15294 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4955438 | 0.80 | GRIN1 (0.84) | GRIN1GRIN2BGRIN2DGRIN3BGRIN2A | |
| SCHEMBL4578168 | 0.73 | GRIN1 (1.00) | GRIN1GRIN2BGRIN2DGRIN3BGRIN2A | |
| SCHEMBL4577738 | 0.72 | GRIN2D (0.80) | GRIN1GRIN2BGRIN2DGRIN3BGRIN2A | |
| SCHEMBL4576733 | 0.71 | GRIN2D (0.64) | GRIN1GRIN2BGRIN2DGRIN3BGRIN2A | |
| SCHEMBL4551727 | 0.71 | GRIN1 (1.00) | GRIN1GRIN2BGRIN2DGRIN3BGRIN2A | |
| SCHEMBL4576699 | 0.71 | GRIN1 (0.66) | GRIN1GRIN2BGRIN2DGRIN3BGRIN2A | |
| SCHEMBL27590230 | 0.70 | FAAH (0.64) | GRIN1GRIN2BGRIN2DGRIN3BGRIN2A | |
| SCHEMBL4576966 | 0.70 | FAAH (0.61) | GRIN1GRIN2BGRIN2DGRIN3BGRIN2A | |
| SCHEMBL4577421 | 0.69 | GRIN1 (0.82) | GRIN1GRIN2BGRIN2DGRIN3BGRIN2A | |
| SCHEMBL4577722 | 0.69 | GRIN2D (0.70) | GRIN1GRIN2BGRIN2DGRIN3BGRIN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1409477-B1 | PIPERIDINE DERIVATIVES AS NMDA RECEPTOR ANTAGONISTS | RICHTER GEDEON NYRT (HU) | 2008-09-17 | — | — | EP | claimed |