Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.65 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.65 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | MAN2A1 | Q16706 | 1/20 | 0.42 |
| ▸ | MAN1B1 | Q9UKM7 | 1/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 2/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | MC4R | P32245 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3316343 | 0.85 | GAA (0.49) | GAAL3MBTL1MEN1KMT2AKDM1A | |
| SCHEMBL28217900 | 0.83 | GAA (0.68) | GAAL3MBTL1MEN1KMT2APOLB | |
| SCHEMBL25668625 | 0.83 | GAA (0.68) | GAAL3MBTL1MEN1KMT2APOLB | |
| SCHEMBL28217901 | 0.83 | GAA (0.68) | GAAL3MBTL1MEN1KMT2APOLB | |
| SCHEMBL664938 | 0.82 | GAA (0.85) | GAAL3MBTL1MEN1KMT2APOLB | |
| SCHEMBL27818229 | 0.82 | GAA (0.85) | GAAL3MBTL1MEN1KMT2APOLB | |
| SCHEMBL3314991 | 0.81 | ADRB2 (0.54) | GAAL3MBTL1MEN1KMT2ACYP2D6 | |
| SCHEMBL4153139 | 0.81 | GAA (0.71) | GAAL3MBTL1MEN1KMT2APOLB | |
| SCHEMBL6023381 | 0.80 | SLC6A4 (0.44) | GAAL3MBTL1MEN1KMT2ALMNA | |
| SCHEMBL3314353 | 0.79 | KDM1A (0.51) | GAAL3MBTL1MEN1KMT2AATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080027035-A1 | Dpp-Iv Inhibitors | GRAFFINITY PHARMACEUTICALS AG (DE) | 2008-01-31 | — | — | US | disclosed |
| EP-1613304-B1 | DPP-IV INHIBITORS | SANTHERA PHARMACEUTICALS CH (CH) | 2007-09-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080027035-A1 | Dpp-Iv Inhibitors | DPP4, DPP7, DPP3 | GAA 315/4885L3MBTL1 1900/4885MEN1 1822/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.