Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 18/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL437431 | 0.82 | DGAT1 (0.54) | DGAT1 | |
| Hydrochloric Acid SCHEMBL441108 | 0.81 | DGAT1 (0.57) | DGAT1 | |
| SCHEMBL438785 | 0.80 | DGAT1 (0.59) | DGAT1 | |
| Hydrochloric Acid SCHEMBL442990 | 0.79 | DGAT1 (0.58) | DGAT1 | |
| SCHEMBL437867 | 0.79 | DGAT1 (0.55) | DGAT1 | |
| SCHEMBL407255 | 0.77 | DGAT1 (0.67) | DGAT1 | |
| Hydrochloric Acid SCHEMBL437866 | 0.76 | DGAT1 (0.66) | DGAT1 | |
| SCHEMBL4910831 | 0.75 | DGAT1 (0.71) | DGAT1 | |
| SCHEMBL463394 | 0.75 | DGAT1 (0.58) | DGAT1 | |
| Hydrochloric Acid SCHEMBL462631 | 0.75 | DGAT1 (0.58) | DGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008011130-A2 | AMIDE COMPOUNDS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-01-24 | — | — | WO | disclosed |