Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | DHFR | P00374 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5316072 | 0.88 | RECQL (0.37) | RECQLMAPTDHFR | |
| SCHEMBL4955540 | 0.86 | RECQL (0.36) | RECQLMAPTNPSR1 | |
| SCHEMBL4955274 | 0.75 | IDO1 (0.37) | MAPTNPSR1DHFR | |
| SCHEMBL4955153 | 0.75 | IDO1 (0.37) | MAPTNPSR1DHFR | |
| SCHEMBL5270904 | 0.75 | KDM4E (0.39) | RECQLMAPTNPSR1 | |
| SCHEMBL4951850 | 0.73 | CYP3A4 (0.37) | RECQL | |
| SCHEMBL4956832 | 0.72 | NPSR1 (0.36) | RECQLMAPTNPSR1DHFR | |
| SCHEMBL4951478 | 0.72 | DHFR (0.40) | MAPTDHFR | |
| SCHEMBL4913815 | 0.71 | DHFR (0.38) | MAPTNPSR1DHFR | |
| SCHEMBL3532871 | 0.71 | RECQL (0.53) | RECQLMAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7371264-B2 | Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof | THE PROCTER & GAMBLE COMPANY (US) | 2008-05-13 | — | — | US | claimed |
| US-7371264-B2 | Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof | THE PROCTER & GAMBLE COMPANY (US) | 2008-05-13 | — | — | US | disclosed |
| US-20060042026-A1 | Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof | THE PROCTER & GAMBLE COMPANY (US) | 2006-03-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060042026-A1 | Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof | KRT18, KDM5A, KDM5C | RECQL 3163/4885MAPT 1139/4885NPSR1 4526/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.